regionReport is a R package for generating detailed interactive reports from regions of the genome. The report includes quality-control checks, an overview of the results, an interactive table of the genomic regions, and reproducibility information. regionReport can easily be expanded with report templates for other specialized analyses. In particular, regionReport has an extensive report template for exploring derfinder results from annotation-agnostic RNA-seq differential expression analyses. regionReport is freely available via Bioconductor at bioconductor.org/packages/release/bioc/html/regionReport.html .