New Results
A rapid and tunable method to temporally control Cas9 expression enables the identification of essential genes and the interrogation of functional gene interactions in vitro and in vivo
Serif Senturk, Nitin H. Shirole, Dawid D. Nowak, Vincenzo Corbo, Alexander Vaughan, David A. Tuveson, Lloyd C. Trotman, Adam Kepecs, Frank Stegmeier, Raffaella Sordella
doi: https://doi.org/10.1101/023366
Serif Senturk
1Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724
Nitin H. Shirole
1Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724
Dawid D. Nowak
1Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724
Vincenzo Corbo
1Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724
Alexander Vaughan
1Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724
David A. Tuveson
1Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724
Lloyd C. Trotman
1Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724
Adam Kepecs
1Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724
Frank Stegmeier
2Novartis Institute for BioMedical Research 250 Massachusetts Avenue, 3C-302 Cambridge, MA 02139
Raffaella Sordella
1Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY 11724
Article usage
Posted July 28, 2015.
A rapid and tunable method to temporally control Cas9 expression enables the identification of essential genes and the interrogation of functional gene interactions in vitro and in vivo
Serif Senturk, Nitin H. Shirole, Dawid D. Nowak, Vincenzo Corbo, Alexander Vaughan, David A. Tuveson, Lloyd C. Trotman, Adam Kepecs, Frank Stegmeier, Raffaella Sordella
bioRxiv 023366; doi: https://doi.org/10.1101/023366
A rapid and tunable method to temporally control Cas9 expression enables the identification of essential genes and the interrogation of functional gene interactions in vitro and in vivo
Serif Senturk, Nitin H. Shirole, Dawid D. Nowak, Vincenzo Corbo, Alexander Vaughan, David A. Tuveson, Lloyd C. Trotman, Adam Kepecs, Frank Stegmeier, Raffaella Sordella
bioRxiv 023366; doi: https://doi.org/10.1101/023366
Subject Area
Subject Areas
- Biochemistry (11736)
- Bioengineering (8746)
- Bioinformatics (29186)
- Biophysics (14964)
- Cancer Biology (12084)
- Cell Biology (17401)
- Clinical Trials (138)
- Developmental Biology (9418)
- Ecology (14176)
- Epidemiology (2067)
- Evolutionary Biology (18299)
- Genetics (12235)
- Genomics (16793)
- Immunology (11863)
- Microbiology (28066)
- Molecular Biology (11580)
- Neuroscience (60925)
- Paleontology (451)
- Pathology (1870)
- Pharmacology and Toxicology (3238)
- Physiology (4956)
- Plant Biology (10422)
- Synthetic Biology (2883)
- Systems Biology (7338)
- Zoology (1650)