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History
- September 25, 2016.
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The copyright holder for this preprint is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. All rights reserved. No reuse allowed without permission.
Author Information
- Manuel A. Rivas1,2,
- Jukka Koskela1,3,
- Hailiang Huang1,3,
- Christine Stevens1,
- Brandon E. Avila1,3,
- Talin Haritunians4,
- Benjamin M. Neale1,3,
- Mitja Kurki1,3,
- Andrea Ganna1,3,
- Daniel Graham1,
- Benjamin Glaser5,
- Inga Peter6,
- Gil Atzmon7,8,
- Nir Barzilai7,
- Adam P. Levine9,
- Elena Schiff9,
- Nikolas Pontikos9,10,
- Ben Weisburd1,3,
- Konrad J. Karczewski1,3,
- Eric V. Minikel1,3,
- Britt-Sabina Petersen11,
- Laurent Beaugerie12,
- Philippe Seksik12,
- Jacques Cosnes12,
- Stefan Schreiber13,
- Bernd Bokemeyer14,
- Johannes Bethge13,
- NIDDK IBD Genetics consortium,
- T2D-GENES consortium,
- Graham Heap15,
- Tariq Ahmad16,
- Vincent Plagnol10,
- Anthony W. Segal9,
- Stephan Targan4,
- Dan Turner17,
- Paivi Saavalainen18,
- Martti Farkkila19,
- Kimmo Kontula20,
- Matti Pirinen21,22,
- Aarno Palotie1,21,23,
- Steven R. Brant24,25,
- Richard H. Duerr26,27,
- Mark S. Silverberg28,
- John D. Rioux29,30,
- Rinse K. Weersma31,
- Andre Franke11,
- Daniel G. MacArthur1,3,
- Chaim Jalas32,
- Harry Sokol12,
- Ramnik J. Xavier1,33,
- Ann Pulver34,
- Judy H. Cho35,
- Dermot P.B. McGovern4 and
- Mark J. Daly1,3
- 1Medical and Population Genetics, Broad Institute, Cambridge, MA, USA
- 2Department of Biomedical Data Science, Stanford, CA, USA
- 3Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA
- 4F. Widjaja Foundation Inflammatory Bowel and Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, California, USA
- 5Hadassah-Hebrew University Medical Center, Endocrinology and Metabolism Service Department of Internal Medicine, Jerusalem, Israel
- 6Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, USA
- 7Department of Genetics and Medicine, Albert Einstein College of Medicine, Bronx, NY, USA
- 8Faculty of Natural Sciences, University of Haifa, Haifa, Israel
- 9Division of Medicine, University College London, London, UK
- 10UCL Genetics Institute, University College London, London, UK
- 11Institute of Clinical Molecular Biology, Christian-Albrechts-University of Kiel, Kiel, Germany
- 12Gastroenterology Department, Saint-Antoine Hospital, AP-HP, UPMC Univ Paris 06, Paris, France
- 13Department of Internal Medicine, University Hospital Schleswig-Holstein, Kiel, Germany
- 14Gastroenterology Practice, Minden, Germany
- 15IBD Pharmacogenetics, Royal Devon and Exeter NHS Trust, Exeter, UK
- 16Peninsula College of Medicine and Dentistry, Exeter, UK
- 17Juliet Keidan Institute of Pediatric Gastroenterology and Nutrition, Shaare Zedek Medical Center, The Hebrew University of Jerusalem, Jerusalem, Israel
- 18Department of Medical Genetics, Biomedicum Helsinki, University of Helsinki, Helsinki, Finland
- 19Department of Medicine, Division of Gastroenterology, Helsinki University Hospital, Helsinki, Finland
- 20Department of Medicine, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
- 21Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland
- 22Department of Mathematics and Statistics, University of Helsinki, Helsinki, Finland
- 23Department of Neurology, Massachusetts General Hospital, Boston, MA, USA
- 24Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
- 25Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
- 26Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA.
- 27Department of Human Genetics, University of Pittsburgh Graduate School of Public Health, Pittsburgh, Pennsylvania, USA.
- 28Inflammatory Bowel Disease Centre, Mount Sinai Hospital, Toronto, Ontario, Canada
- 29Research Center, Montreal Heart Institute, Montréal, Québec, Canada
- 30Department of Medicine, Université de Montréal, Montréal, Québec, Canada
- 31Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, The Netherlands
- 32Bonei Olam, Center for Rare Jewish Genetic Disorders, Brooklyn, NY, USA.
- 33Gastrointestinal Unit and Center for the Study of Inflammatory Bowel Disease and Center for Computational and Integrative Biology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
- 34Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
- 35Icahn School of Medicine at Mount Sinai, Dr Henry D. Janowitz Division of Gastroenterology, New York, New York, USA
- 34Section of Digestive Diseases, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut, USA,
- 35Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio, USA,
- 36Department of Pathobiology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA,
- 37Division of Gastroenterology, Royal Victoria Hospital, Montréal, Québec, Canada,
- 38Inflammatory Bowel Disease Group, Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada,
- 39Department of Transplantation and Liver Surgery, University of Helsinki, Helsinki, Finland,
- 40Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, USA,
- 41Division of Pediatric Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, Ontario, Canada,
- 42Department of Public Health Sciences, University of Chicago, Chicago, Illinois, USA,
- 43Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY
- Correspondence: mrivas{at}stanford.edu, Dermot.McGovern{at}cshs.org, judy.cho{at}mssm.edu and mjdaly{at}atgu.mgh.harvard.edu