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Linkage disequilibrium dependent architecture of human complex traits reveals action of negative selection
Steven Gazal, Hilary K. Finucane, Nicholas A Furlotte, Po-Ru Loh, Pier Francesco Palamara, Xuanyao Liu, Armin Schoech, Brendan Bulik-Sullivan, Benjamin M Neale, Alexander Gusev, Alkes L. Price
doi: https://doi.org/10.1101/082024
Steven Gazal
1Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
2Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Hilary K. Finucane
1Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
2Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
3Department of Mathematics, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Nicholas A Furlotte
423andMe, Inc. Mountain View, California, USA.
Po-Ru Loh
1Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
2Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Pier Francesco Palamara
1Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
2Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Xuanyao Liu
1Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
2Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Armin Schoech
1Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
2Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
5Department of Systems Biology, Harvard Medical School, Boston, Massachusetts, USA
Brendan Bulik-Sullivan
2Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
6Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Benjamin M Neale
2Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
6Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
7Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.
Alexander Gusev
1Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
2Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
Alkes L. Price
1Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
2Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.
8Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Article usage
Posted April 03, 2017.
Linkage disequilibrium dependent architecture of human complex traits reveals action of negative selection
Steven Gazal, Hilary K. Finucane, Nicholas A Furlotte, Po-Ru Loh, Pier Francesco Palamara, Xuanyao Liu, Armin Schoech, Brendan Bulik-Sullivan, Benjamin M Neale, Alexander Gusev, Alkes L. Price
bioRxiv 082024; doi: https://doi.org/10.1101/082024
Linkage disequilibrium dependent architecture of human complex traits reveals action of negative selection
Steven Gazal, Hilary K. Finucane, Nicholas A Furlotte, Po-Ru Loh, Pier Francesco Palamara, Xuanyao Liu, Armin Schoech, Brendan Bulik-Sullivan, Benjamin M Neale, Alexander Gusev, Alkes L. Price
bioRxiv 082024; doi: https://doi.org/10.1101/082024
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