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Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures
View ORCID ProfileYoshitaka Hiruma, Andre Koch, Nazila Hazraty, Foteini Tsakou, View ORCID ProfileRené H. Medema, View ORCID ProfileRobbie P. Joosten, View ORCID ProfileAnastassis Perrakis
doi: https://doi.org/10.1101/112086
Yoshitaka Hiruma
1Division of Biochemistry and Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands.
Andre Koch
2Cell Biology, Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands.
Nazila Hazraty
1Division of Biochemistry and Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands.
Foteini Tsakou
1Division of Biochemistry and Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands.
René H. Medema
2Cell Biology, Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands.
Robbie P. Joosten
1Division of Biochemistry and Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands.
Anastassis Perrakis
1Division of Biochemistry and Netherlands Cancer Institute, 1066 CX Amsterdam, the Netherlands.
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Posted July 18, 2017.
Understanding inhibitor resistance in Mps1 kinase through novel biophysical assays and structures
Yoshitaka Hiruma, Andre Koch, Nazila Hazraty, Foteini Tsakou, René H. Medema, Robbie P. Joosten, Anastassis Perrakis
bioRxiv 112086; doi: https://doi.org/10.1101/112086
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