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The genetic architecture of osteoarthritis: insights from UK Biobank
Eleni Zengini, Konstantinos Hatzikotoulas, Ioanna Tachmazidou, Julia Steinberg, Fernando P. Hartwig, Lorraine Southam, Sophie Hackinger, Cindy G. Boer, Unnur Styrkarsdottir, Daniel Suveges, Britt Killian, Arthur Gilly, Thorvaldur Ingvarsson, Helgi Jonsson, George C. Babis, Andrew McCaskie, Andre G. Uitterlinden, Joyce B. J. van Meurs, Unnur Thorsteinsdottir, Kari Stefansson, George Davey Smith, Mark J. Wilkinson, Eleftheria Zeggini
doi: https://doi.org/10.1101/174755
Eleni Zengini
1Department of Oncology and Metabolism, University of Sheffield, Sheffield S10 2RX, United Kingdom
25th Psychiatric Department, Dromokaiteio Psychiatric Hospital, Athens 124 61, Greece
Konstantinos Hatzikotoulas
3Human Genetics, Wellcome Trust Sanger Institute, Hinxton CB10 1HH, United Kingdom
Ioanna Tachmazidou
3Human Genetics, Wellcome Trust Sanger Institute, Hinxton CB10 1HH, United Kingdom
4GSK, R&D Target Sciences, Medicines Research Centre, Stevenage SG1 2NY, United Kingdom
Julia Steinberg
3Human Genetics, Wellcome Trust Sanger Institute, Hinxton CB10 1HH, United Kingdom
5Cancer Research Division, Cancer Council NSW, Sydney NSW 2011, Australia
Fernando P. Hartwig
6Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas 96020-220, Brazil
7Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, United Kingdom
Lorraine Southam
3Human Genetics, Wellcome Trust Sanger Institute, Hinxton CB10 1HH, United Kingdom
8Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, United Kingdom
Sophie Hackinger
3Human Genetics, Wellcome Trust Sanger Institute, Hinxton CB10 1HH, United Kingdom
Cindy G. Boer
9Department of Internal Medicine, Erasmus MC, Rotterdam, Netherlands
Unnur Styrkarsdottir
10deCODE genetics, Reykjavik 101, Iceland
Daniel Suveges
3Human Genetics, Wellcome Trust Sanger Institute, Hinxton CB10 1HH, United Kingdom
Britt Killian
3Human Genetics, Wellcome Trust Sanger Institute, Hinxton CB10 1HH, United Kingdom
Arthur Gilly
3Human Genetics, Wellcome Trust Sanger Institute, Hinxton CB10 1HH, United Kingdom
Thorvaldur Ingvarsson
11Department of Orthopaedic Surgery, Akureyri Hospital, Akureyri 600, Iceland
12Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland
13Institution of Health Science, University of Akureyri, Akureyri 600.0, Iceland
Helgi Jonsson
12Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland
14Department of Medicine, Landspitali, The National University Hospital of Iceland, Reykjavik 101, Iceland
George C. Babis
15National and Kapodistrian University of Athens, 2nd Department of Orthopaedic Surgery Konstantopouleio General Hospital, Athens, Greece
Andrew McCaskie
16Division of Trauma & Orthopaedic Surgery; Department of Surgery; University of Cambridge; Box 180, Addenbrooke’s Hospital, Cambridge CB2 0QQ, United Kingdom
Andre G. Uitterlinden
9Department of Internal Medicine, Erasmus MC, Rotterdam, Netherlands
Joyce B. J. van Meurs
9Department of Internal Medicine, Erasmus MC, Rotterdam, Netherlands
Unnur Thorsteinsdottir
10deCODE genetics, Reykjavik 101, Iceland
12Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland
Kari Stefansson
10deCODE genetics, Reykjavik 101, Iceland
12Faculty of Medicine, University of Iceland, Reykjavik 101, Iceland
George Davey Smith
7Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, United Kingdom
Mark J. Wilkinson
1Department of Oncology and Metabolism, University of Sheffield, Sheffield S10 2RX, United Kingdom
17School of Social and Community Medicine, University of Bristol, Bristol BS8 2BN, United Kingdom
Eleftheria Zeggini
3Human Genetics, Wellcome Trust Sanger Institute, Hinxton CB10 1HH, United Kingdom
Article usage
Posted August 11, 2017.
The genetic architecture of osteoarthritis: insights from UK Biobank
Eleni Zengini, Konstantinos Hatzikotoulas, Ioanna Tachmazidou, Julia Steinberg, Fernando P. Hartwig, Lorraine Southam, Sophie Hackinger, Cindy G. Boer, Unnur Styrkarsdottir, Daniel Suveges, Britt Killian, Arthur Gilly, Thorvaldur Ingvarsson, Helgi Jonsson, George C. Babis, Andrew McCaskie, Andre G. Uitterlinden, Joyce B. J. van Meurs, Unnur Thorsteinsdottir, Kari Stefansson, George Davey Smith, Mark J. Wilkinson, Eleftheria Zeggini
bioRxiv 174755; doi: https://doi.org/10.1101/174755
The genetic architecture of osteoarthritis: insights from UK Biobank
Eleni Zengini, Konstantinos Hatzikotoulas, Ioanna Tachmazidou, Julia Steinberg, Fernando P. Hartwig, Lorraine Southam, Sophie Hackinger, Cindy G. Boer, Unnur Styrkarsdottir, Daniel Suveges, Britt Killian, Arthur Gilly, Thorvaldur Ingvarsson, Helgi Jonsson, George C. Babis, Andrew McCaskie, Andre G. Uitterlinden, Joyce B. J. van Meurs, Unnur Thorsteinsdottir, Kari Stefansson, George Davey Smith, Mark J. Wilkinson, Eleftheria Zeggini
bioRxiv 174755; doi: https://doi.org/10.1101/174755
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