PT  - JOURNAL ARTICLE
AU  - James M Wilson
AU  - Walter Brediger
AU  - Tom Albright
AU  - Julie Smith-Gagen
TI  - Reanalysis of the Anthrax Epidemic in Rhodesia, 1978-84
AID  - 10.1101/053769
DP  - 2016 Jan 01
TA  - bioRxiv
PG  - 053769
4099  - http://biorxiv.org/content/early/2016/05/17/053769.short
4100  - http://biorxiv.org/content/early/2016/05/17/053769.full
AB  - In the mid-1980s, the largest epidemic of anthrax of the last 200 years was documented in a little known series of studies by Davies in The Central African Journal of Medicine. This epidemic involved thousands of cattle and 10,738 human cases with 200 fatalities in Rhodesia during the Counterinsurgency. Grossly unusual epidemiological features were noted that, to this day, have not been definitively explained. This study performed a historical reanalysis of the data to reveal an estimated geographic involvement of 245,750 km2, with 171,990 cattle and 17,199 human cases. Geospatial time series analysis is suggestive of multiple, independent geotemporal foci of anthrax introduced via an unknown mechanism rather than re-emergence from native endemic foci.