RT Journal Article
SR Electronic
T1 Haplotype block dynamics in hybrid populations
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 058107
DO 10.1101/058107
A1 Thijs Janzen
A1 Arne W. Nolte
A1 Arne Traulsen
YR 2016
UL http://biorxiv.org/content/early/2016/06/09/058107.abstract
AB When species originate through hybridization, the genomes of the ancestral species are blended together. Over time genomic blocks that originate from either one of the ancestral species accumulate in the hybrid genome through genetic recombination. Modeling the accumulation of ancestry blocks can elucidate processes and patterns of genomic admixture. However, previous models have ignored ancestry block dynamics for chromosomes that consist of a discrete, finite number of chromosomal elements. Here we present an analytical treatment of the dynamics of the mean number of blocks over time, for continuous and discrete chromosomes, in finite and infinite populations. We describe the mean number of haplotype blocks as a universal function dependent on population size, the number of genomic elements per chromosome, the number of recombination events, and the initial relative frequency of the ancestral species.