RT Journal Article
SR Electronic
T1 Novel blaKPC-carrying species identified in the hospital environment
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 069856
DO 10.1101/069856
A1 Hang T.T. Phan
A1 Zoie Aiken
A1 Oluwafemi Akinremi
A1 Julie Cawthorne
A1 Andrew Dodgson
A1 Angela Downes
A1 Matthew Ellington
A1 Ryan George
A1 Amy Mathers
A1 Nicole Stoesser
A1 Stephanie Thomas
A1 on behalf of the TRACE Investigators’ Group
YR 2016
UL http://biorxiv.org/content/early/2016/08/16/069856.abstract
AB blaKPC, encoding one of five dominant global carbapenemase families, is increasingly identified in environmental species difficult to characterize using routine diagnostic methods, with epidemiological and clinical implications. During environmental hospital infection prevention and control investigations (Manchester, UK) we used whole genome sequencing to confirm species identification for isolates infrequently associated with blaKPC and/or difficult to classify by MALDI-ToF. Four previously undescribed blaKPC-carrying species were identified from the hospital environment, including a putative, novel Enterobacter species.