PT - JOURNAL ARTICLE AU - Nan Xiao AU - Qing-Song Xu AU - Miao-Zhu Li TI - hdnom: Building Nomograms for Penalized Cox Models with High-Dimensional Survival Data AID - 10.1101/065524 DP - 2016 Jan 01 TA - bioRxiv PG - 065524 4099 - http://biorxiv.org/content/early/2016/08/23/065524.short 4100 - http://biorxiv.org/content/early/2016/08/23/065524.full AB - Summary We developed hdnom, an R package for survival modeling with high-dimensional data. The package is the first free and open-source software package that streamlines the workflow of penalized Cox model building, validation, calibration, comparison, and nomogram visualization, with nine types of penalized Cox regression methods fully supported. A web application and an online prediction tool maker are offered to enhance interac-tivity and flexibility in high-dimensional survival analysis.Availability The hdnom R package is available from CRAN: https://cran.r-project.org/package=hdnom under GPL. The hdnom web application can be accessed at http://hdnom.io. The web application maker is available from http://hdnom.org/appmaker. The hdnom project website: http://hdnom.org.Contact qsxu{at}csu.edu.cn or miaozhu.li{at}duke.edu