PT  - JOURNAL ARTICLE
AU  - David C. Krakauer
AU  - Lydia Müller
AU  - Sonja J. Prohaska
AU  - Peter F. Stadler
TI  - Design Specifications for Cellular Regulation
AID  - 10.1101/081729
DP  - 2016 Jan 01
TA  - bioRxiv
PG  - 081729
4099  - http://biorxiv.org/content/early/2016/10/18/081729.short
4100  - http://biorxiv.org/content/early/2016/10/18/081729.full
AB  - A critical feature of all cellular processes is the ability to control the rate of gene or protein expression and metabolic flux in changing environments through regulatory feedback. We review the many ways that regulation is represented through causal, logical and dynamical components. Formalizing the nature of these components promotes effective comparison among distinct regulatory networks and provides a common framework for the potential design and control of regulatory systems in synthetic biology.