TY - JOUR T1 - Design Specifications for Cellular Regulation JF - bioRxiv DO - 10.1101/081729 SP - 081729 AU - David C. Krakauer AU - Lydia Müller AU - Sonja J. Prohaska AU - Peter F. Stadler Y1 - 2016/01/01 UR - http://biorxiv.org/content/early/2016/10/18/081729.abstract N2 - A critical feature of all cellular processes is the ability to control the rate of gene or protein expression and metabolic flux in changing environments through regulatory feedback. We review the many ways that regulation is represented through causal, logical and dynamical components. Formalizing the nature of these components promotes effective comparison among distinct regulatory networks and provides a common framework for the potential design and control of regulatory systems in synthetic biology. ER -