PT - JOURNAL ARTICLE AU - Semir Zeki AU - Oliver Y. Chén TI - The Bayesian-Laplacian Brain AID - 10.1101/094516 DP - 2016 Jan 01 TA - bioRxiv PG - 094516 4099 - http://biorxiv.org/content/early/2016/12/19/094516.short 4100 - http://biorxiv.org/content/early/2016/12/19/094516.full AB - We discuss here what we feel could be an improvement in future discussions of the brain acting as a Bayesian-Laplacian system, by distinguishing between two classes of priors on which the brain's inferential systems operate. In one category are biological priors (β priors) and in the other artefactual ones (α priors). We argue that β priors are inherited or acquired very rapidly after birth and are much more resistant to varying experiences than α priors which, being continuously acquired at various stages throughout post-natal life, are much more accommodating of, and hospitable to, new experiences. Consequently, the posteriors generated from the two sets of priors are likewise different, being more constrained (i.e., precise) for β than for α priors.When, to silent sessions devoted to brain thought, We summon up formulations from endeavours past, And sigh the lack of many a principle that we sought, Because those principles were, in our mind, mis-cast, Lo, for all priors should not be tied in a single Bayesian knot For biological and artefactual priors each have a separate slotA (posterior) Bayesian-Laplacian adaptation from Shakespeare’s Sonnets