TY - JOUR T1 - How much research is spurred when a gene is associated with a complex disease? JF - bioRxiv DO - 10.1101/106773 SP - 106773 AU - Travis J. Struck AU - Brian K. Mannakee AU - Ryan N. Gutenkunst Y1 - 2017/01/01 UR - http://biorxiv.org/content/early/2017/02/07/106773.abstract N2 - The impact of genome-wide association studies (GWAS) on biomedical research output was quantitatively evaluated. GWAS have not changed the historical skew of publications toward genes involved in Mendelian diseases, but genes newly implicated by GWAS in complex disease do experience a modest increase in publication activity. The impact of GWAS on biomedical research into individual genes is declining, however, even as the rate of new GWAS associations increases. ER -