RT Journal Article
SR Electronic
T1 An oscillopathic approach to developmental dyslexia: from genes to speech processing
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 108704
DO 10.1101/108704
A1 Miguel Jiménez-Bravo
A1 Victoria Marrero
A1 Antonio Benítez-Burraco
YR 2017
UL http://biorxiv.org/content/early/2017/02/14/108704.abstract
AB Developmental dyslexia is a heterogeneous condition entailing problems with reading and spelling. Several genes have been linked or associated to the disease, many of which contribute to the development and function of brain areas that are important for auditory and phonological processing. Nonetheless, a clear link between genes, the brain, and the symptoms of dyslexia is still pending. The goal of this paper is contributing to bridge this gap. With this aim, we have focused on how the dyslexic brain fails to process speech sounds and reading cues. We have adopted an oscillatory perspective, according to which dyslexia results from a deficient integration of different brain rhythms during reading/spellings tasks. Moreover, we show that some candidates for this condition are related to brain rhythms. This approach should help gain a better understanding of the aetiology and the clinical presentation of developmental dyslexia, but also achieve an earlier and more accurate diagnosis of the disease.