PT  - JOURNAL ARTICLE
AU  - Marina B. Chiappero
AU  - Imanol Cabaña
AU  - Gladys E. Calderón
AU  - Cristina N. Gardenal
TI  - Genetic variability in the promoter region of TNF-α gene in the reservoir of Junin virus, Calomys musculinus (Rodentia, Cricetidae)
AID  - 10.1101/113688
DP  - 2017 Jan 01
TA  - bioRxiv
PG  - 113688
4099  - http://biorxiv.org/content/early/2017/03/04/113688.short
4100  - http://biorxiv.org/content/early/2017/03/04/113688.full
AB  - In this study, we assessed the genetic variability of the promoter region of TNF-α gene in three natural populations of the cricetid rodent Calomys musculinus. This species is the natural reservoir of Junin virus, the etiological agent of Argentine Hemorrhagic fever. We found different levels of variability and varying signatures of natural selection in populations with different epidemiological histories.