RT Journal Article SR Electronic T1 Gamma and beta bursts during working memory read-out suggest roles in its volitional control JF bioRxiv FD Cold Spring Harbor Laboratory SP 122598 DO 10.1101/122598 A1 Mikael Lundqvist A1 Pawel Herman A1 Melissa R. Warden A1 Scott L. Brincat A1 Earl K. Miller YR 2017 UL http://biorxiv.org/content/early/2017/03/31/122598.abstract AB Working memory (WM) activity is not as stationary or sustained as previously thought. There are brief bursts of gamma (∼55–120 Hz) and beta (∼20–35 Hz) oscillations, the former linked to stimulus information in spiking. We examine these dynamics in relation to read-out from WM, which is still not well understood. Monkeys held a sequence of two objects and had to decide if they matched a subsequent sequence. Changes in the balance of beta/gamma suggested their role in WM control. In anticipation of having to use an object for the match decision, there was an increase in spiking information about that object along with an increase in gamma and a decrease in beta. When an object was no longer needed, beta increased and gamma as well as spiking information about that object decreased. Deviations from these dynamics predicted behavioral errors. Thus, turning up or down beta could regulate gamma and the information in working memory.