PT  - JOURNAL ARTICLE
AU  - Wesley Spiller
AU  - Neil M. Davies
AU  - Tom M. Palmer
TI  - Software Application Profile: mrrobust - a tool for performing two-sample summary Mendelian randomization analyses
AID  - 10.1101/142125
DP  - 2017 Jan 01
TA  - bioRxiv
PG  - 142125
4099  - http://biorxiv.org/content/early/2017/05/25/142125.short
4100  - http://biorxiv.org/content/early/2017/05/25/142125.full
AB  - Motivation In recent years Mendelian randomization analysis using summary data from genome-wide association studies has become a popular approach for investigating causal relationships in epidemiology. The mrrobust Stata package implements several of the recently developed methods.Implementation mrrobust is freely available as a Stata package.General Features The package includes inverse variance weighted estimation, as well as a range of median and MR-Egger estimation methods. Using mrrobust, plots can be constructed visualising each estimate either individually or simultaneously. The package also provides statistics such as , which are useful in assessing attenuation bias in causal estimates.Availability The software is freely available from GitHub [https://raw.github.com/remlapmot/mrrobust/master/].