PT  - JOURNAL ARTICLE
AU  - T. Jeffrey Cole
AU  - Michael S. Brewer
TI  - FUSTr: a tool to find gene Families Under Selection in Transcriptomes
AID  - 10.1101/146951
DP  - 2017 Jan 01
TA  - bioRxiv
PG  - 146951
4099  - http://biorxiv.org/content/early/2017/06/07/146951.1.short
4100  - http://biorxiv.org/content/early/2017/06/07/146951.1.full
AB  - FUSTr is a tool for finding genes in transcriptomic datasets under strong positive selection that automatically detects isoform designation patterns in transcriptome assemblies to maximize phylogenetic independence in downstream analysis. When applied to previously studied spider toxin families as well as simulated data, FUSTr successfully grouped coding sequences into proper gene families as well as correctly identified those under strong positive selection. FUSTr provides a tool capable of utilizing multi-processor high-performance computational facilities and is scalable for large transcriptomic biodiversity datasets.Availability FUSTr is freely available under a GNU license and can be downloaded at https://github.com/tijeco/FUSTr.Contact coleti16{at}students.ecu.edu