PT  - JOURNAL ARTICLE
AU  - Aziz Khan
AU  - Anthony Mathelier
TI  - JASPAR RESTful API: accessing JASPAR data from any programming language
AID  - 10.1101/160184
DP  - 2017 Jan 01
TA  - bioRxiv
PG  - 160184
4099  - http://biorxiv.org/content/early/2017/07/06/160184.short
4100  - http://biorxiv.org/content/early/2017/07/06/160184.full
AB  - JASPAR is a widely used open-access database of curated, non-redundant transcription factor binding profiles. Currently, data from JASPAR can be retrieved as flat files or by using programming language-specific interfaces. Here, we present a programming language-independent application programming interface (API) to access JASPAR data using the Representational State Transfer (REST) architecture. The REST API enables programmatic access to JASPAR by most programming languages and returns data in seven widely used formats. Further, it provides an endpoint to infer the TF binding profile(s) likely bound by a given DNA binding domain protein sequence. Additionally, it provides an interactive browsable interface for bioinformatics tool developers. The REST API is implemented in Python using the Django REST Framework. It is accessible at http://hfaistos.uio.no:8000/api/and the source code is freely available at https://bitbucket.org/CBGR/jaspar under GPL v3 license.Note that the current URLs are available during the peer-review process; the API will later be available at http://jaspar.genereg.net/api/.