RT Journal Article
SR Electronic
T1 GAS Power Calculator: web-based power calculator for genetic association studies
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 164343
DO 10.1101/164343
A1 Jennifer Li Johnson
A1 Gonçalo R. Abecasis
YR 2017
UL http://biorxiv.org/content/early/2017/07/17/164343.abstract
AB Motivation: Statistical power calculations are crucial in designing genetic association studies. They help guide tradeoffs between large sample sizes and detailed assessments of genotype and phenotype, help determine which studies are viable, and help interpret research findings. To facilitate widespread use of power analysis in the design and interpretation of genetic studies, it is important to enable users to calculate power and visualize the effect of different models and design choices in convenient, interactive tools that are easily accessible.Results: We developed the Genetic Association Study (GAS) Power Calculator to provide users with a simple interface that can be compute the power of genetic association studies in a convenient browser based interface.Availability: The GAS Power Calculator can be accessed from the web interface at http://csg.sph.umich.edu/abecasis/gas_power_calculator/. Source code is available at https://github.com/jenlij/GAS-power-calculator.