RT Journal Article
SR Electronic
T1 Creating a highly directional anti-tumor immunity
JF bioRxiv
FD Cold Spring Harbor Laboratory
SP 169227
DO 10.1101/169227
A1 Vyacheslav A. Buts
A1 Klavdiya P. Skibenko
YR 2017
UL http://biorxiv.org/content/early/2017/07/28/169227.abstract
AB A simple method of creating a highly directional anti-tumor immunity is proposed. It is shown that under the influence of ultrasound of small and medium intensity, it is possible to tear off antigens from the cell surface (surface antigens (SA)). It was found that the immunogenicity of these SAs is not less than the immunogenicity of intact cells. These results give a new opportunity for creating specific, acute-directed immunity against malignant tumors.