PT - JOURNAL ARTICLE AU - Moses Olubusuyi Adewumi AU - Temitope Oluwasegun Cephas Faleye AU - Johnson Adekunle Adeniji TI - The fallacy of identification by neutralization in the light of cytopathology nonproducing enterovirus strains AID - 10.1101/173419 DP - 2017 Jan 01 TA - bioRxiv PG - 173419 4099 - http://biorxiv.org/content/early/2017/08/08/173419.short 4100 - http://biorxiv.org/content/early/2017/08/08/173419.full AB - We describe the characterization of an enterovirus isolate recovered from untreated raw sewage in Ibadan, southwest Nigeria in 2010. The isolate was neutralized by specific antisera and consequently identified as Echovirus 7 (E7). Subsequent molecular characterization showed the isolate to be a mixture of E7 and Coxsackievirus A24 (CV-A24) thereby suggesting the CV-A24 strain to be non-cytopathology producing. Further molecular analysis suggested that the CV-A24 might have recombined with a Sabin poliovirus 2 (PV2) in its non-structural region. This is the first description of a Nigerian CV-A24 strain.