RT Journal Article SR Electronic T1 Multi-Unit Activity contains information about spatial stimulus structure in mouse primary visual cortex JF bioRxiv FD Cold Spring Harbor Laboratory SP 029108 DO 10.1101/029108 A1 Marie Tolkiehn A1 Simon R. Schultz YR 2015 UL http://biorxiv.org/content/early/2015/10/14/029108.abstract AB This study investigates the spatial and directional tuning of Multi-Unit Activity (MUA) in mouse primary visual cortex and how MUA can reflect spatiotemporal structures contained in moving gratings. Analysis of multi-shank laminar electrophysiological recordings from mouse primary visual cortex indicates a directional preference for moving gratings around 180°, while preferred spatial frequency peaks around 0.02 cycles per degree, which is similar as reported in single-unit studies. Using only features from MUA, we further achieved a significant performance in decoding spatial frequency or direction of moving gratings, with average decoding performances of up to 58.54% for 8 directions, and 44% correctly identified spatial frequencies against chance level of 16.7%.