TY - JOUR T1 - Incoherent feedforward motifs as immune change detectors JF - bioRxiv DO - 10.1101/035600 SP - 035600 AU - Eduardo D. Sontag Y1 - 2015/01/01 UR - http://biorxiv.org/content/early/2015/12/30/035600.abstract N2 - We speculate that incoherent feedforward loops may be phenomenologically involved in self/nonself discrimination in immune-infection and immune-tumor interactions, acting as “change detectors”. In turn, this may result in logarithmic sensing (Weber phenomenon) and even scale invariance (fold-change detection). ER -