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Vitamin C activates young LINE-1 elements in mouse embryonic stem cells via H3K9me3 demethylation.
Cheng KCL, Frost JM, Sánchez-Luque FJ, García-Canãdas M, Taylor D, Yang WR, Irayanar B, Sampath S, Patani H, Agger K, Helin K, Ficz G, Burns KH, Ewing A, García-Pérez JL, Branco MR. Cheng KCL, et al. Among authors: garcia canadas m. Epigenetics Chromatin. 2023 Oct 16;16(1):39. doi: 10.1186/s13072-023-00514-6. Epigenetics Chromatin. 2023. PMID: 37845773 Free PMC article.
LINE-1 Retrotransposition Assays in Embryonic Stem Cells.
Garcia-Cañadas M, Sanchez-Luque FJ, Sanchez L, Rojas J, Garcia Perez JL. Garcia-Cañadas M, et al. Methods Mol Biol. 2023;2607:257-309. doi: 10.1007/978-1-0716-2883-6_13. Methods Mol Biol. 2023. PMID: 36449167
LINE-1 Evasion of Epigenetic Repression in Humans.
Sanchez-Luque FJ, Kempen MHC, Gerdes P, Vargas-Landin DB, Richardson SR, Troskie RL, Jesuadian JS, Cheetham SW, Carreira PE, Salvador-Palomeque C, García-Cañadas M, Muñoz-Lopez M, Sanchez L, Lundberg M, Macia A, Heras SR, Brennan PM, Lister R, Garcia-Perez JL, Ewing AD, Faulkner GJ. Sanchez-Luque FJ, et al. Among authors: garcia canadas m. Mol Cell. 2019 Aug 8;75(3):590-604.e12. doi: 10.1016/j.molcel.2019.05.024. Epub 2019 Jun 20. Mol Cell. 2019. PMID: 31230816 Free article.
A new human embryonic cell type associated with activity of young transposable elements allows definition of the inner cell mass.
Singh M, Kondrashkina AM, Widmann TJ, Cortes JL, Bansal V, Wang J, Römer C, Garcia-Canadas M, Garcia-Perez JL, Hurst LD, Izsvák Z. Singh M, et al. Among authors: garcia canadas m. PLoS Biol. 2023 Jun 20;21(6):e3002162. doi: 10.1371/journal.pbio.3002162. eCollection 2023 Jun. PLoS Biol. 2023. PMID: 37339119 Free PMC article.
RNase H2, mutated in Aicardi-Goutières syndrome, promotes LINE-1 retrotransposition.
Benitez-Guijarro M, Lopez-Ruiz C, Tarnauskaitė Ž, Murina O, Mian Mohammad M, Williams TC, Fluteau A, Sanchez L, Vilar-Astasio R, Garcia-Canadas M, Cano D, Kempen MH, Sanchez-Pozo A, Heras SR, Jackson AP, Reijns MA, Garcia-Perez JL. Benitez-Guijarro M, et al. Among authors: garcia canadas m. EMBO J. 2018 Aug 1;37(15):e98506. doi: 10.15252/embj.201798506. Epub 2018 Jun 29. EMBO J. 2018. PMID: 29959219 Free PMC article.
Analysis of LINE-1 expression in human pluripotent cells.
Muñoz-Lopez M, Garcia-Cañadas M, Macia A, Morell S, Garcia-Perez JL. Muñoz-Lopez M, et al. Among authors: garcia canadas m. Methods Mol Biol. 2012;873:113-25. doi: 10.1007/978-1-61779-794-1_7. Methods Mol Biol. 2012. PMID: 22528351
Localization of a bacterial group II intron-encoded protein in human cells.
Reinoso-Colacio M, García-Rodríguez FM, García-Cañadas M, Amador-Cubero S, García Pérez JL, Toro N. Reinoso-Colacio M, et al. Among authors: garcia canadas m. Sci Rep. 2015 Aug 5;5:12716. doi: 10.1038/srep12716. Sci Rep. 2015. PMID: 26244523 Free PMC article.
Mobilization of LINE-1 retrotransposons is restricted by Tex19.1 in mouse embryonic stem cells.
MacLennan M, García-Cañadas M, Reichmann J, Khazina E, Wagner G, Playfoot CJ, Salvador-Palomeque C, Mann AR, Peressini P, Sanchez L, Dobie K, Read D, Hung CC, Eskeland R, Meehan RR, Weichenrieder O, García-Pérez JL, Adams IR. MacLennan M, et al. Among authors: garcia canadas m. Elife. 2017 Aug 14;6:e26152. doi: 10.7554/eLife.26152. Elife. 2017. PMID: 28806172 Free PMC article.
Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells.
Klawitter S, Fuchs NV, Upton KR, Muñoz-Lopez M, Shukla R, Wang J, Garcia-Cañadas M, Lopez-Ruiz C, Gerhardt DJ, Sebe A, Grabundzija I, Merkert S, Gerdes P, Pulgarin JA, Bock A, Held U, Witthuhn A, Haase A, Sarkadi B, Löwer J, Wolvetang EJ, Martin U, Ivics Z, Izsvák Z, Garcia-Perez JL, Faulkner GJ, Schumann GG. Klawitter S, et al. Among authors: garcia canadas m. Nat Commun. 2016 Jan 8;7:10286. doi: 10.1038/ncomms10286. Nat Commun. 2016. PMID: 26743714 Free PMC article.
13 results