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Cross-ancestry, cell-type-informed atlas of gene, isoform, and splicing regulation in the developing human brain.
Wen C, Margolis M, Dai R, Zhang P, Przytycki PF, Vo DD, Bhattacharya A, Matoba N, Jiao C, Kim M, Tsai E, Hoh C, Aygün N, Walker RL, Chatzinakos C, Clarke D, Pratt H, Consortium P, Peters MA, Gerstein M, Daskalakis NP, Weng Z, Jaffe AE, Kleinman JE, Hyde TM, Weinberger DR, Bray NJ, Sestan N, Geschwind DH, Roeder K, Gusev A, Pasaniuc B, Stein JL, Love MI, Pollard KS, Liu C, Gandal MJ. Wen C, et al. Among authors: consortium p. medRxiv [Preprint]. 2023 Mar 6:2023.03.03.23286706. doi: 10.1101/2023.03.03.23286706. medRxiv. 2023. PMID: 36945630 Free PMC article. Preprint.
Genomic regulatory elements active in the developing human brain are notably enriched in genetic risk for neuropsychiatric disorders, including autism spectrum disorder (ASD), schizophrenia, and bipolar disorder. ...
Genomic regulatory elements active in the developing human brain are notably enriched in genetic risk for neuropsychiatric disorders, …
A polymorphism in the promoter of FRAS1 is a candidate SNP associated with metastatic prostate cancer.
Wang V, Geybels MS, Jordahl KM, Gerke T, Hamid A, Penney KL, Markt SC, Freedman M, Pomerantz M, Lee GM, Rana H, Börnigen D, Rebbeck TR, Huttenhower C, Eeles RA, Stanford JL, Consortium P, Berndt SI, Claessens F, Sørensen KD, Park JY, Vega A, Usmani N, Mucci L, Sweeney CJ. Wang V, et al. Among authors: consortium p. Prostate. 2021 Jul;81(10):683-693. doi: 10.1002/pros.24148. Epub 2021 May 6. Prostate. 2021. PMID: 33956343 Free PMC article.
METHODS: Using a Bayesian approach leveraging NFkappaB biology with integration of publicly available datasets we used a previously defined genome-wide functional association network specific to NFkappaB and lethal prostate cancer. A dense-module-searching method identifie …
METHODS: Using a Bayesian approach leveraging NFkappaB biology with integration of publicly available datasets we used a previously defined …
Coronavirus and Paramyxovirus Shedding by Bats in a Cave and Buildings in Ethiopia.
Lane JK, Negash Y, Randhawa N, Kebede N, Wells H, Ayalew G, Anthony SJ, Smith B, Goldstein T, Kassa T, Mazet JAK, Consortium P, Smith WA. Lane JK, et al. Among authors: consortium p. Ecohealth. 2022 Jun;19(2):216-232. doi: 10.1007/s10393-022-01590-y. Epub 2022 Jun 30. Ecohealth. 2022. PMID: 35771308 Free PMC article.
Validation of Enhancer Regions in Primary Human Neural Progenitor Cells using Capture STARR-seq.
Gaynor-Gillett SC, Cheng L, Shi M, Liu J, Wang G, Spector M, Flaherty M, Wall M, Hwang A, Gu M, Chen Z, Chen Y, Consortium P, Moran JR, Zhang J, Lee D, Gerstein M, Geschwind D, White KP. Gaynor-Gillett SC, et al. Among authors: consortium p. bioRxiv [Preprint]. 2024 Mar 18:2024.03.14.585066. doi: 10.1101/2024.03.14.585066. bioRxiv. 2024. PMID: 38562832 Free PMC article. Preprint.
Genome-wide association studies (GWAS) and expression analyses implicate noncoding regulatory regions as harboring risk factors for psychiatric disease, but functional characterization of these regions remains limited. ...
Genome-wide association studies (GWAS) and expression analyses implicate noncoding regulatory regions as harboring risk factors for p …