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Page 1
eIF2B-catalyzed nucleotide exchange and phosphoregulation by the integrated stress response.
Science. 2019 May 3;364(6439):491-495. doi: 10.1126/science.aaw2922.
Science. 2019.
PMID: 31048491
Free PMC article.
Rescue of conformational dynamics in enzyme catalysis by directed evolution.
Otten R, Liu L, Kenner LR, Clarkson MW, Mavor D, Tawfik DS, Kern D, Fraser JS.
Otten R, et al. Among authors: kenner lr.
Nat Commun. 2018 Apr 3;9(1):1314. doi: 10.1038/s41467-018-03562-9.
Nat Commun. 2018.
PMID: 29615624
Free PMC article.
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Systematic functional prioritization of protein posttranslational modifications.
Beltrao P, Albanèse V, Kenner LR, Swaney DL, Burlingame A, Villén J, Lim WA, Fraser JS, Frydman J, Krogan NJ.
Beltrao P, et al. Among authors: kenner lr.
Cell. 2012 Jul 20;150(2):413-25. doi: 10.1016/j.cell.2012.05.036.
Cell. 2012.
PMID: 22817900
Free PMC article.
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Conformational variation of proteins at room temperature is not dominated by radiation damage.
Russi S, González A, Kenner LR, Keedy DA, Fraser JS, van den Bedem H.
Russi S, et al. Among authors: kenner lr.
J Synchrotron Radiat. 2017 Jan 1;24(Pt 1):73-82. doi: 10.1107/S1600577516017343. Epub 2017 Jan 1.
J Synchrotron Radiat. 2017.
PMID: 28009548
Free PMC article.
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Determination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting.
Mavor D, Barlow K, Thompson S, Barad BA, Bonny AR, Cario CL, Gaskins G, Liu Z, Deming L, Axen SD, Caceres E, Chen W, Cuesta A, Gate RE, Green EM, Hulce KR, Ji W, Kenner LR, Mensa B, Morinishi LS, Moss SM, Mravic M, Muir RK, Niekamp S, Nnadi CI, Palovcak E, Poss EM, Ross TD, Salcedo EC, See SK, Subramaniam M, Wong AW, Li J, Thorn KS, Conchúir SÓ, Roscoe BP, Chow ED, DeRisi JL, Kortemme T, Bolon DN, Fraser JS.
Mavor D, et al. Among authors: kenner lr.
Elife. 2016 Apr 25;5:e15802. doi: 10.7554/eLife.15802.
Elife. 2016.
PMID: 27111525
Free PMC article.
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Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance.
Mavor D, Barlow KA, Asarnow D, Birman Y, Britain D, Chen W, Green EM, Kenner LR, Mensa B, Morinishi LS, Nelson CA, Poss EM, Suresh P, Tian R, Arhar T, Ary BE, Bauer DP, Bergman ID, Brunetti RM, Chio CM, Dai SA, Dickinson MS, Elledge SK, Helsell CVM, Hendel NL, Kang E, Kern N, Khoroshkin MS, Kirkemo LL, Lewis GR, Lou K, Marin WM, Maxwell AM, McTigue PF, Myers-Turnbull D, Nagy TL, Natale AM, Oltion K, Pourmal S, Reder GK, Rettko NJ, Rohweder PJ, Schwarz DMC, Tan SK, Thomas PV, Tibble RW, Town JP, Tsai MK, Ugur FS, Wassarman DR, Wolff AM, Wu TS, Bogdanoff D, Li J, Thorn KS, O'Conchúir S, Swaney DL, Chow ED, Madhani HD, Redding S, Bolon DN, Kortemme T, DeRisi JL, Kampmann M, Fraser JS.
Mavor D, et al. Among authors: kenner lr.
Biol Open. 2018 Jul 23;7(7):bio036103. doi: 10.1242/bio.036103.
Biol Open. 2018.
PMID: 30037883
Free PMC article.
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Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.
Keedy DA, Kenner LR, Warkentin M, Woldeyes RA, Hopkins JB, Thompson MC, Brewster AS, Van Benschoten AH, Baxter EL, Uervirojnangkoorn M, McPhillips SE, Song J, Alonso-Mori R, Holton JM, Weis WI, Brunger AT, Soltis SM, Lemke H, Gonzalez A, Sauter NK, Cohen AE, van den Bedem H, Thorne RE, Fraser JS.
Keedy DA, et al. Among authors: kenner lr.
Elife. 2015 Sep 30;4:e07574. doi: 10.7554/eLife.07574.
Elife. 2015.
PMID: 26422513
Free PMC article.
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