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A review of the frequencies of Plasmodium falciparum Kelch 13 artemisinin resistance mutations in Africa.
Ndwiga L, Kimenyi KM, Wamae K, Osoti V, Akinyi M, Omedo I, Ishengoma DS, Duah-Quashie N, Andagalu B, Ghansah A, Amambua-Ngwa A, Tukwasibwe S, Tessema SK, Karema C, Djimde AA, Dondorp AM, Raman J, Snow RW, Bejon P, Ochola-Oyier LI. Ndwiga L, et al. Among authors: kimenyi km. Int J Parasitol Drugs Drug Resist. 2021 Aug;16:155-161. doi: 10.1016/j.ijpddr.2021.06.001. Epub 2021 Jun 10. Int J Parasitol Drugs Drug Resist. 2021. PMID: 34146993 Free PMC article. Review.
Targeted Amplicon Deep Sequencing for Monitoring Antimalarial Resistance Markers in Western Kenya.
Osoti V, Akinyi M, Wamae K, Kimenyi KM, de Laurent Z, Ndwiga L, Gichuki P, Okoyo C, Kepha S, Mwandawiro C, Kandie R, Bejon P, Snow RW, Ochola-Oyier LI. Osoti V, et al. Among authors: kimenyi km. Antimicrob Agents Chemother. 2022 Apr 19;66(4):e0194521. doi: 10.1128/aac.01945-21. Epub 2022 Mar 10. Antimicrob Agents Chemother. 2022. PMID: 35266823 Free PMC article.
No evidence of P. falciparum K13 artemisinin conferring mutations over a 24-year analysis in Coastal Kenya, but a near complete reversion to chloroquine wild type parasites.
Wamae K, Okanda D, Ndwiga L, Osoti V, Kimenyi KM, Abdi AI, Bejon P, Sutherland C, Ochola-Oyier LI. Wamae K, et al. Among authors: kimenyi km. Antimicrob Agents Chemother. 2019 Sep 9;63(12):e01067-19. doi: 10.1128/AAC.01067-19. Epub 2019 Oct 7. Antimicrob Agents Chemother. 2019. PMID: 31591113 Free PMC article.
11 results