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Page 1
Proteostasis impairment and ALS.
Prog Biophys Mol Biol. 2022 Oct;174:3-27. doi: 10.1016/j.pbiomolbio.2022.06.001. Epub 2022 Jun 15.
Prog Biophys Mol Biol. 2022.
PMID: 35716729
Review.
The pivotal role of ubiquitin-activating enzyme E1 (UBA1) in neuronal health and neurodegeneration.
Lambert-Smith IA, Saunders DN, Yerbury JJ.
Lambert-Smith IA, et al.
Int J Biochem Cell Biol. 2020 Jun;123:105746. doi: 10.1016/j.biocel.2020.105746. Epub 2020 Apr 18.
Int J Biochem Cell Biol. 2020.
PMID: 32315770
Review.
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Addition of exogenous SOD1 aggregates causes TDP-43 mislocalisation and aggregation.
Zeineddine R, Farrawell NE, Lambert-Smith IA, Yerbury JJ.
Zeineddine R, et al. Among authors: lambert smith ia.
Cell Stress Chaperones. 2017 Nov;22(6):893-902. doi: 10.1007/s12192-017-0804-y. Epub 2017 May 30.
Cell Stress Chaperones. 2017.
PMID: 28560609
Free PMC article.
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SOD1A4V aggregation alters ubiquitin homeostasis in a cell model of ALS.
Farrawell NE, Lambert-Smith I, Mitchell K, McKenna J, McAlary L, Ciryam P, Vine KL, Saunders DN, Yerbury JJ.
Farrawell NE, et al. Among authors: lambert smith i.
J Cell Sci. 2018 Jun 12;131(11):jcs209122. doi: 10.1242/jcs.209122.
J Cell Sci. 2018.
PMID: 29748379
Free PMC article.
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Spinal motor neuron protein supersaturation patterns are associated with inclusion body formation in ALS.
Ciryam P, Lambert-Smith IA, Bean DM, Freer R, Cid F, Tartaglia GG, Saunders DN, Wilson MR, Oliver SG, Morimoto RI, Dobson CM, Vendruscolo M, Favrin G, Yerbury JJ.
Ciryam P, et al. Among authors: lambert smith ia.
Proc Natl Acad Sci U S A. 2017 May 16;114(20):E3935-E3943. doi: 10.1073/pnas.1613854114. Epub 2017 Apr 10.
Proc Natl Acad Sci U S A. 2017.
PMID: 28396410
Free PMC article.
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Distinct partitioning of ALS associated TDP-43, FUS and SOD1 mutants into cellular inclusions.
Farrawell NE, Lambert-Smith IA, Warraich ST, Blair IP, Saunders DN, Hatters DM, Yerbury JJ.
Farrawell NE, et al. Among authors: lambert smith ia.
Sci Rep. 2015 Aug 21;5:13416. doi: 10.1038/srep13416.
Sci Rep. 2015.
PMID: 26293199
Free PMC article.
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