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Loss of metal ions, disulfide reduction and mutations related to familial ALS promote formation of amyloid-like aggregates from superoxide dismutase.
Oztug Durer ZA, Cohlberg JA, Dinh P, Padua S, Ehrenclou K, Downes S, Tan JK, Nakano Y, Bowman CJ, Hoskins JL, Kwon C, Mason AZ, Rodriguez JA, Doucette PA, Shaw BF, Valentine JS. Oztug Durer ZA, et al. PLoS One. 2009;4(3):e5004. doi: 10.1371/journal.pone.0005004. Epub 2009 Mar 27. PLoS One. 2009. PMID: 19325915 Free PMC article.