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Page 1
IFITM proteins assist cellular uptake of diverse linked chemotypes.
Lou K, Wassarman DR, Yang T, Paung Y, Zhang Z, O'Loughlin TA, Moore MK, Egan RK, Greninger P, Benes CH, Seeliger MA, Taunton J, Gilbert LA, Shokat KM. Lou K, et al. Among authors: wassarman dr. Science. 2022 Dec 9;378(6624):1097-1104. doi: 10.1126/science.abl5829. Epub 2022 Dec 8. Science. 2022. PMID: 36480603 Free PMC article.
The language of bacterial defences expands.
Wassarman DR, Kranzusch PJ. Wassarman DR, et al. Nature. 2023 Oct;622(7984):705-706. doi: 10.1038/d41586-023-03149-5. Nature. 2023. PMID: 37853200 No abstract available.
Tissue-restricted inhibition of mTOR using chemical genetics.
Wassarman DR, Bankapalli K, Pallanck LJ, Shokat KM. Wassarman DR, et al. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2204083119. doi: 10.1073/pnas.2204083119. Epub 2022 Sep 12. Proc Natl Acad Sci U S A. 2022. PMID: 36095197 Free PMC article.
Repurposing Hsp90 inhibitors as antibiotics targeting histidine kinases.
Vo CD, Shebert HL, Zikovich S, Dryer RA, Huang TP, Moran LJ, Cho J, Wassarman DR, Falahee BE, Young PD, Gu GH, Heinl JF, Hammond JW, Jackvony TN, Frederick TE, Blair JA. Vo CD, et al. Among authors: wassarman dr. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5235-5244. doi: 10.1016/j.bmcl.2017.10.036. Epub 2017 Oct 19. Bioorg Med Chem Lett. 2017. PMID: 29110989 Free article.
Robust Sequence Determinants of α-Synuclein Toxicity in Yeast Implicate Membrane Binding.
Newberry RW, Arhar T, Costello J, Hartoularos GC, Maxwell AM, Naing ZZC, Pittman M, Reddy NR, Schwarz DMC, Wassarman DR, Wu TS, Barrero D, Caggiano C, Catching A, Cavazos TB, Estes LS, Faust B, Fink EA, Goldman MA, Gomez YK, Gordon MG, Gunsalus LM, Hoppe N, Jaime-Garza M, Johnson MC, Jones MG, Kung AF, Lopez KE, Lumpe J, Martyn C, McCarthy EE, Miller-Vedam LE, Navarro EJ, Palar A, Pellegrino J, Saylor W, Stephens CA, Strickland J, Torosyan H, Wankowicz SA, Wong DR, Wong G, Redding S, Chow ED, DeGrado WF, Kampmann M. Newberry RW, et al. Among authors: wassarman dr. ACS Chem Biol. 2020 Aug 21;15(8):2137-2153. doi: 10.1021/acschembio.0c00339. Epub 2020 Aug 12. ACS Chem Biol. 2020. PMID: 32786289 Free PMC article.
A Drosophila model of closed head traumatic brain injury.
Katzenberger RJ, Loewen CA, Wassarman DR, Petersen AJ, Ganetzky B, Wassarman DA. Katzenberger RJ, et al. Among authors: wassarman dr. Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):E4152-9. doi: 10.1073/pnas.1316895110. Epub 2013 Oct 14. Proc Natl Acad Sci U S A. 2013. PMID: 24127584 Free PMC article.
Extending chemical perturbations of the ubiquitin fitness landscape in a classroom setting reveals new constraints on sequence tolerance.
Mavor D, Barlow KA, Asarnow D, Birman Y, Britain D, Chen W, Green EM, Kenner LR, Mensa B, Morinishi LS, Nelson CA, Poss EM, Suresh P, Tian R, Arhar T, Ary BE, Bauer DP, Bergman ID, Brunetti RM, Chio CM, Dai SA, Dickinson MS, Elledge SK, Helsell CVM, Hendel NL, Kang E, Kern N, Khoroshkin MS, Kirkemo LL, Lewis GR, Lou K, Marin WM, Maxwell AM, McTigue PF, Myers-Turnbull D, Nagy TL, Natale AM, Oltion K, Pourmal S, Reder GK, Rettko NJ, Rohweder PJ, Schwarz DMC, Tan SK, Thomas PV, Tibble RW, Town JP, Tsai MK, Ugur FS, Wassarman DR, Wolff AM, Wu TS, Bogdanoff D, Li J, Thorn KS, O'Conchúir S, Swaney DL, Chow ED, Madhani HD, Redding S, Bolon DN, Kortemme T, DeRisi JL, Kampmann M, Fraser JS. Mavor D, et al. Among authors: wassarman dr. Biol Open. 2018 Jul 23;7(7):bio036103. doi: 10.1242/bio.036103. Biol Open. 2018. PMID: 30037883 Free PMC article.
Novosphingobium aromaticivorans uses a Nu-class glutathione S-transferase as a glutathione lyase in breaking the β-aryl ether bond of lignin.
Kontur WS, Bingman CA, Olmsted CN, Wassarman DR, Ulbrich A, Gall DL, Smith RW, Yusko LM, Fox BG, Noguera DR, Coon JJ, Donohue TJ. Kontur WS, et al. Among authors: wassarman dr. J Biol Chem. 2018 Apr 6;293(14):4955-4968. doi: 10.1074/jbc.RA117.001268. Epub 2018 Feb 15. J Biol Chem. 2018. PMID: 29449375 Free PMC article.