User profiles for A. C. McHardy
Alice Carolyn McHardyHelmholtz Centre for Infection Research, Germany Verified email at helmholtz-hzi.de Cited by 27021 |
The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitamins
…, K Huthmacher, R Krämer, B Linke, AC McHardy… - Journal of …, 2003 - Elsevier
… Phenotypic analysis and enzyme activity measurements of a C. glutamicum mutant with a
deletion of dapF resulted in the unequivocal identification of this gene (Hartmann et al., 2003). …
deletion of dapF resulted in the unequivocal identification of this gene (Hartmann et al., 2003). …
[HTML][HTML] Eleven grand challenges in single-cell data science
The recent boom in microfluidics and combinatorial indexing strategies, combined with low
sequencing costs, has empowered single-cell sequencing technology. Thousands—or even …
sequencing costs, has empowered single-cell sequencing technology. Thousands—or even …
Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies
Whether the human fetus and the prenatal intrauterine environment (amniotic fluid and
placenta) are stably colonized by microbial communities in a healthy pregnancy remains a …
placenta) are stably colonized by microbial communities in a healthy pregnancy remains a …
The subsystems approach to genome annotation and its use in the project to annotate 1000 genomes
…, M Kubal, N Larsen, B Linke, AC McHardy… - Nucleic acids …, 2005 - academic.oup.com
… Two forms of yngF (encoding the methylcrotonyl-CoA carboxylase biotin-containing subunit
(EC 6.4.1.4) were observed—the most common form, a fusion of biotin carboxylase and a C-…
(EC 6.4.1.4) were observed—the most common form, a fusion of biotin carboxylase and a C-…
Metagenomic and functional analysis of hindgut microbiota of a wood-feeding higher termite
From the standpoints of both basic research and biotechnology, there is considerable interest
in reaching a clearer understanding of the diversity of biological mechanisms employed …
in reaching a clearer understanding of the diversity of biological mechanisms employed …
[PDF][PDF] Structure and function of the bacterial root microbiota in wild and domesticated barley
The microbial communities inhabiting the root interior of healthy plants, as well as the
rhizosphere, which consists of soil particles firmly attached to roots, engage in symbiotic …
rhizosphere, which consists of soil particles firmly attached to roots, engage in symbiotic …
Functional overlap of the Arabidopsis leaf and root microbiota
Roots and leaves of healthy plants host taxonomically structured bacterial assemblies, and
members of these communities contribute to plant growth and health. We established …
members of these communities contribute to plant growth and health. We established …
Defining seasonal marine microbial community dynamics
Here we describe, the longest microbial time-series analyzed to date using high-resolution
16S rRNA tag pyrosequencing of samples taken monthly over 6 years at a temperate marine …
16S rRNA tag pyrosequencing of samples taken monthly over 6 years at a temperate marine …
GenDB—an open source genome annotation system for prokaryote genomes
… of certain features of coding sequences, such as TMHMM (16) for the prediction of α‐helical
transmembrane regions, SignalP (17) for signal peptide prediction, or CoBias (ACMcHardy …
transmembrane regions, SignalP (17) for signal peptide prediction, or CoBias (ACMcHardy …
[HTML][HTML] Critical assessment of metagenome interpretation—a benchmark of metagenomics software
… (a–c) Fractions of reference genomes assembled by each assembler for all genomes (a),
genomes with ANI < 95% (b) and genomes with ANI ≥95% (c). Colors indicate results from the …
genomes with ANI < 95% (b) and genomes with ANI ≥95% (c). Colors indicate results from the …