User profiles for A. E. Bergues-Pupo

Ana Elisa Bergues Pupo

BIMSB, Max Delbrück Center
Verified email at mdc-berlin.de
Cited by 370

[HTML][HTML] Molecular mechanics of coiled coils loaded in the shear geometry

M Goktas, C Luo, RMA Sullan, AE Bergues-Pupo… - Chemical …, 2018 - pubs.rsc.org
Coiled coils are important nanomechanical building blocks in biological and biomimetic
materials. A mechanistic molecular understanding of their structural response to mechanical …

Role of the central cations in the mechanical unfolding of DNA and RNA G-quadruplexes

AE Bergues-Pupo, JR Arias-Gonzalez… - Nucleic acids …, 2015 - academic.oup.com
AE Bergues-Pupo also acknowledges the financial support of Universidad de Zaragoza and
Banco Santander. AF acknowledges the EPSRC project GALE EP/K020633/1. Funding for …

Fortified coiled coils: Enhancing mechanical stability with lactam or metal staples

…, AD de Araujo, AE BerguesPupo… - Angewandte Chemie …, 2021 - Wiley Online Library
Coiled coils (CCs) are powerful supramolecular building blocks for biomimetic materials,
increasingly used for their mechanical properties. Here, we introduce helix‐inducing …

[HTML][HTML] Structural determinants of coiled coil mechanics

P López-García, M Goktas, AE Bergues-Pupo… - Physical Chemistry …, 2019 - pubs.rsc.org
The natural abundance of coiled coil (CC) motifs in the cytoskeleton and the extracellular
matrix suggests that CCs play a crucial role in the bidirectional mechanobiochemical signaling …

[HTML][HTML] Trimeric coiled coils expand the range of strength, toughness and dynamics of coiled coil motifs under shear

AE Bergues-Pupo, KG Blank, R Lipowsky… - Physical Chemistry …, 2018 - pubs.rsc.org
Coiled coils are widespread protein motifs in nature, and promising building blocks for bio-inspired
nanomaterials and nanoscale force sensors. Detailed structural insight into their …

[HTML][HTML] Analytical and numerical solutions of the potential and electric field generated by different electrode arrays in a tumor tissue under electrotherapy

AE Bergues Pupo, JB Reyes… - Biomedical engineering …, 2011 - Springer
Background Electrotherapy is a relatively well established and efficient method of tumor
treatment. In this paper we focus on analytical and numerical calculations of the potential and …

Modeling the interaction of DNA with alternating fields

AE Bergues-Pupo, JM Bergues, F Falo - Physical Review E, 2013 - APS
We study the influence of a terahertz field on thermal properties of DNA molecules. A
Peyrard-Bishop-Dauxois model with the inclusion of a solvent interaction term is considered. The …

Unzipping of DNA under the influence of external fields

AE Bergues-Pupo, JM Bergues, F Falo - Physica A: Statistical Mechanics …, 2014 - Elsevier
We study the features on the unzipping process of a modified version of the Peyrard–Bishop–Dauxois
model. We show that the inclusion of a barrier in the on-site potential allows for the …

[HTML][HTML] Mesoscopic model for DNA G-quadruplex unfolding

AE Bergues-Pupo, I Gutierrez, JR Arias-Gonzalez… - Scientific Reports, 2017 - nature.com
Genomes contain rare guanine-rich sequences capable of assembling into four-stranded
helical structures, termed G-quadruplexes, with potential roles in gene regulation and …

Resonant optimization in the mechanical unzipping of DNA

AE Bergues-Pupo, F Falo, A Fiasconaro - Europhysics Letters, 2014 - iopscience.iop.org
The mechanical separation of the double-stranded DNA in single-molecule experiments is
of fundamental importance in the understanding of the replication or transcription processes. …