User profiles for A. E. Bergues-Pupo
Ana Elisa Bergues PupoBIMSB, Max Delbrück Center Verified email at mdc-berlin.de Cited by 370 |
[HTML][HTML] Molecular mechanics of coiled coils loaded in the shear geometry
Coiled coils are important nanomechanical building blocks in biological and biomimetic
materials. A mechanistic molecular understanding of their structural response to mechanical …
materials. A mechanistic molecular understanding of their structural response to mechanical …
Role of the central cations in the mechanical unfolding of DNA and RNA G-quadruplexes
AE Bergues-Pupo, JR Arias-Gonzalez… - Nucleic acids …, 2015 - academic.oup.com
… AE Bergues-Pupo also acknowledges the financial support of Universidad de Zaragoza and
Banco Santander. AF acknowledges the EPSRC project GALE EP/K020633/1. Funding for …
Banco Santander. AF acknowledges the EPSRC project GALE EP/K020633/1. Funding for …
Fortified coiled coils: Enhancing mechanical stability with lactam or metal staples
…, AD de Araujo, AE Bergues‐Pupo… - Angewandte Chemie …, 2021 - Wiley Online Library
Coiled coils (CCs) are powerful supramolecular building blocks for biomimetic materials,
increasingly used for their mechanical properties. Here, we introduce helix‐inducing …
increasingly used for their mechanical properties. Here, we introduce helix‐inducing …
[HTML][HTML] Structural determinants of coiled coil mechanics
P López-García, M Goktas, AE Bergues-Pupo… - Physical Chemistry …, 2019 - pubs.rsc.org
The natural abundance of coiled coil (CC) motifs in the cytoskeleton and the extracellular
matrix suggests that CCs play a crucial role in the bidirectional mechanobiochemical signaling …
matrix suggests that CCs play a crucial role in the bidirectional mechanobiochemical signaling …
[HTML][HTML] Trimeric coiled coils expand the range of strength, toughness and dynamics of coiled coil motifs under shear
Coiled coils are widespread protein motifs in nature, and promising building blocks for bio-inspired
nanomaterials and nanoscale force sensors. Detailed structural insight into their …
nanomaterials and nanoscale force sensors. Detailed structural insight into their …
[HTML][HTML] Analytical and numerical solutions of the potential and electric field generated by different electrode arrays in a tumor tissue under electrotherapy
AE Bergues Pupo, JB Reyes… - Biomedical engineering …, 2011 - Springer
Background Electrotherapy is a relatively well established and efficient method of tumor
treatment. In this paper we focus on analytical and numerical calculations of the potential and …
treatment. In this paper we focus on analytical and numerical calculations of the potential and …
Modeling the interaction of DNA with alternating fields
We study the influence of a terahertz field on thermal properties of DNA molecules. A
Peyrard-Bishop-Dauxois model with the inclusion of a solvent interaction term is considered. The …
Peyrard-Bishop-Dauxois model with the inclusion of a solvent interaction term is considered. The …
Unzipping of DNA under the influence of external fields
We study the features on the unzipping process of a modified version of the Peyrard–Bishop–Dauxois
model. We show that the inclusion of a barrier in the on-site potential allows for the …
model. We show that the inclusion of a barrier in the on-site potential allows for the …
[HTML][HTML] Mesoscopic model for DNA G-quadruplex unfolding
Genomes contain rare guanine-rich sequences capable of assembling into four-stranded
helical structures, termed G-quadruplexes, with potential roles in gene regulation and …
helical structures, termed G-quadruplexes, with potential roles in gene regulation and …
Resonant optimization in the mechanical unzipping of DNA
The mechanical separation of the double-stranded DNA in single-molecule experiments is
of fundamental importance in the understanding of the replication or transcription processes. …
of fundamental importance in the understanding of the replication or transcription processes. …