Several studies have shown that promoters of protein-coding genes are origins of pervasive
non-coding RNA transcription and can initiate transcription in both directions. However, only …

RNA-binding proteins play a key role in the regulation of all aspects of RNA metabolism, from
the synthesis of RNA to its decay. Protein-RNA interactions have been thought to be mostly …

The crucial participation of cellular RNA‐binding proteins (RBPs) in virtually all steps of virus
infection has been known for decades. However, most of the studies characterizing this …

Active human promoters produce promoter-upstream transcripts (PROMPTs). Why these
RNAs are coupled to decay, whereas their neighboring promoter-downstream mRNAs are not, …

Due to the complexity of the protocols and a limited knowledge of the nature of microbial
communities, simulating metagenomic sequences plays an important role in testing the …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). SARS-CoV-2 relies on cellular RNA-binding proteins (RBPs) to …

The compendium of RNA-binding proteins (RBPs) has been greatly expanded by the
development of RNA-interactome capture (RIC). However, it remained unknown if the complement …

Recent research has uncovered extensive variability in the boundaries of transcript isoforms,
yet the functional consequences of this variation remain largely unexplored. Here, we …

The use of alternative poly(A) sites is common and affects the post-transcriptional fate of mRNA,
including its stability, subcellular localization and translation. Here, we present a method …

Mammalian transcriptomes are complex and formed by extensive promoter activity. In
addition, gene promoters are largely divergent and initiate transcription of reverse-oriented …