[HTML][HTML] Episodic sexual transmission of HIV revealed by molecular phylodynamics
…, A Rambaut, A Pozniak, AJ Leigh Brown - PLoS …, 2008 - journals.plos.org
… Leigh Brown … Leigh Brown … Citation: Lewis F, Hughes GJ, Rambaut A, Pozniak A, Leigh
Brown AJ (2008) Episodic Sexual Transmission of HIV Revealed by Molecular Phylodynamics. …
Brown AJ (2008) Episodic Sexual Transmission of HIV Revealed by Molecular Phylodynamics. …
Heterogeneous clearance rates of long-lived lymphocytes infected with HIV: intrinsic stability predicts lifelong persistence
…, DM Smith, AJ Leigh-Brown… - Proceedings of the …, 2003 - National Acad Sciences
Viral replication and latently infected cellular reservoirs persist in HIV-infected patients
achieving undetectable plasma virus levels with potent antiretroviral therapy. We exploited a …
achieving undetectable plasma virus levels with potent antiretroviral therapy. We exploited a …
Phylodynamics of infectious disease epidemics
…, SL Kosakovsky Pond, MJ Ward, AJ Leigh Brown… - Genetics, 2009 - academic.oup.com
We present a formalism for unifying the inference of population size from genetic sequences
and mathematical models of infectious disease in populations. Virus phylogenies have …
and mathematical models of infectious disease in populations. Virus phylogenies have …
The global transmission network of HIV-1
JO Wertheim, AJ Leigh Brown, NL Hepler… - The Journal of …, 2014 - academic.oup.com
… see Leigh Brown et al [12] for an alternative approach), wasting the considerable computational
effort expended to infer the complete phylogeny. Furthermore, the relationship between …
effort expended to infer the complete phylogeny. Furthermore, the relationship between …
Transmission network parameters estimated from HIV sequences for a nationwide epidemic
Background. Many studies of sexual behavior have shown that individuals vary greatly in
their number of sexual partners over time, but it has proved difficult to obtain parameter …
their number of sexual partners over time, but it has proved difficult to obtain parameter …
HIV-TRACE (TRAnsmission Cluster Engine): a tool for large scale molecular epidemiology of HIV-1 and other rapidly evolving pathogens
…, S Weaver, AJ Leigh Brown… - Molecular biology …, 2018 - academic.oup.com
In modern applications of molecular epidemiology, genetic sequence data are routinely
used to identify clusters of transmission in rapidly evolving pathogens, most notably HIV-1. …
used to identify clusters of transmission in rapidly evolving pathogens, most notably HIV-1. …
[HTML][HTML] Molecular phylodynamics of the heterosexual HIV epidemic in the United Kingdom
The heterosexual risk group has become the largest HIV infected group in the United Kingdom
during the last 10 years, but little is known of the network structure and dynamics of viral …
during the last 10 years, but little is known of the network structure and dynamics of viral …
[HTML][HTML] An evolutionary model-based algorithm for accurate phylogenetic breakpoint mapping and subtype prediction in HIV-1
…, MB Gravenor, AJ Leigh Brown… - PLoS computational …, 2009 - journals.plos.org
Genetically diverse pathogens (such as Human Immunodeficiency virus type 1, HIV-1) are
frequently stratified into phylogenetically or immunologically defined subtypes for …
frequently stratified into phylogenetically or immunologically defined subtypes for …
Dynamics of the emergence and establishment of a newly dominant genotype of Japanese encephalitis virus throughout Asia
In recent years, genotype I (GI) of Japanese encephalitis virus (JEV) has displaced genotype
III (GIII) as the dominant virus genotype throughout Asia. In this study, the largest collection …
III (GIII) as the dominant virus genotype throughout Asia. In this study, the largest collection …
Evolution of envelope sequences of human immunodeficiency virus type 1 in cellular reservoirs in the setting of potent antiviral therapy
HF Günthard, SDW Frost, AJ Leigh-Brown… - Journal of …, 1999 - Am Soc Microbiol
In human immunodeficiency virus (HIV)-infected patients treated with potent antiretroviral
therapy, the persistence of latently infected cells may reflect the long decay half-life of this …
therapy, the persistence of latently infected cells may reflect the long decay half-life of this …