User profiles for A. L. Archibald
Alan L. ArchibaldThe Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh Verified email at roslin.ed.ac.uk Cited by 17985 |
[HTML][HTML] Livestock 2.0–genome editing for fitter, healthier, and more productive farmed animals
The human population is growing, and as a result we need to produce more food whilst
reducing the impact of farming on the environment. Selective breeding and genomic selection …
reducing the impact of farming on the environment. Selective breeding and genomic selection …
[HTML][HTML] From FAANG to fork: application of highly annotated genomes to improve farmed animal production
The Food and Agriculture Organisation of the United Nations (FAO) reports that by the year
2050 the global human population is likely to reach 9.7 billion, rising to 11.2 billion by 2100 (…
2050 the global human population is likely to reach 9.7 billion, rising to 11.2 billion by 2100 (…
[HTML][HTML] Analyses of pig genomes provide insight into porcine demography and evolution
For 10,000 years pigs and humans have shared a close and complex relationship. From
domestication to modern breeding practices, humans have shaped the genomes of domestic …
domestication to modern breeding practices, humans have shaped the genomes of domestic …
A regulatory mutation in IGF2 causes a major QTL effect on muscle growth in the pig
…, C Nezer, C Collette, L Moreau, AL Archibald… - Nature, 2003 - nature.com
Most traits and disorders have a multifactorial background indicating that they are controlled
by environmental factors as well as an unknown number of quantitative trait loci (QTLs) 1 , 2 …
by environmental factors as well as an unknown number of quantitative trait loci (QTLs) 1 , 2 …
[HTML][HTML] Design of a high density SNP genotyping assay in the pig using SNPs identified and characterized by next generation sequencing technology
…, NA Affara, AJ Amaral, AL Archibald… - PloS one, 2009 - journals.plos.org
Background The dissection of complex traits of economic importance to the pig industry
requires the availability of a significant number of genetic markers, such as single nucleotide …
requires the availability of a significant number of genetic markers, such as single nucleotide …
Exome sequencing: current and future perspectives
The completion of a reference genome sequence for humans took more than 200 scientists
more than a decade in a project that cost almost $3 billion to complete (International Human …
more than a decade in a project that cost almost $3 billion to complete (International Human …
Strong signatures of selection in the domestic pig genome
Domestication of wild boar (Sus scrofa) and subsequent selection have resulted in dramatic
phenotypic changes in domestic pigs for a number of traits, including behavior, body …
phenotypic changes in domestic pigs for a number of traits, including behavior, body …
The sheep genome illuminates biology of the rumen and lipid metabolism
Sheep (Ovis aries) are a major source of meat, milk, and fiber in the form of wool and represent
a distinct class of animals that have a specialized digestive organ, the rumen, that carries …
a distinct class of animals that have a specialized digestive organ, the rumen, that carries …
The PiGMaP consortium linkage map of the pig (Sus scrofa)
AL Archibald, CS Haley, JF Brown, S Couperwhite… - Mammalian …, 1995 - Springer
A linkage map of the porcine genome has been developed by segregation analysis of 239
genetic markers. Eighty-one of these markers correspond to known genes. Linkage groups …
genetic markers. Eighty-one of these markers correspond to known genes. Linkage groups …
[HTML][HTML] Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV …
…, T Ait-Ali, CBA Whitelaw, AL Archibald - PLoS …, 2017 - journals.plos.org
Porcine Reproductive and Respiratory Syndrome (PRRS) is a panzootic infectious disease
of pigs, causing major economic losses to the world-wide pig industry. PRRS manifests …
of pigs, causing major economic losses to the world-wide pig industry. PRRS manifests …