In this review we focus on the role of chemokines in discreet areas of innate immunity and
demonstrate that chemokines are key participants to not only the early inflammatory response …

Alternatively activated (M2) macrophages play critical roles in diverse chronic diseases,
including parasite infections, cancer, and allergic responses. However, little is known about the …

Although cellular senescence may be a protective mechanism in modulating proliferative
capacity, fibroblast senescence is now recognized as a key pathogenic mechanism in …

The critical role of angiogenesis in tumor development makes its inhibition a valuable new
approach in therapy, rapidly making anti-angiogenesis a major focus in research. While the …

… Now, Trujillo et al. have identified a marker that differentiates these two patient groups and
… Trujillo et al. hypothesized that TLR9 may contribute to rapidly progressing IPF. Indeed, they …

Background Idiopathic pulmonary fibrosis exhibits differential progression from the time of
diagnosis but the molecular basis for varying progression rates is poorly understood. The aim …

In recent years crowd modeling has become increasingly important both in the computer
games industry and in emergency simulation. This paper discusses some aspects of what has …

The purpose of this study was to develop a technique to evaluate the implant–abutment gap
of an external hexagon implant system as a function of radius. Six implants of 3·75 mm in …

The aberrant fibrotic and repair responses in the lung are major hallmarks of idiopathic
pulmonary fibrosis (IPF). Numerous antifibrotic strategies have been used in the clinic with limited …

Idiopathic pulmonary fibrosis (IPF) is a progressive disease with unremitting extracellular matrix
deposition, leading to a distortion of pulmonary architecture and impaired gas exchange. …