The relationship between intestinal stem cells (ISCs) and the surrounding niche environment
is complex and dynamic. Key factors localized at the base of the crypt are necessary to …

Cutinases are polyester hydrolases that show a remarkable capability to hydrolyze polyethylene
terephthalate (PET) to its monomeric units. This revelation has stimulated research …

Background & Aims The intestinal epithelium is maintained by intestinal stem cells (ISCs),
which produce postmitotic absorptive and secretory epithelial cells. Initial fate specification …

Background & Aims Crohn’s disease is an inflammatory bowel disease that affects the ileum
and is associated with increased cytokines. Although interleukin (IL)6, IL17, IL21, and IL22 …

In a continuing search for “curcuminoid (CUR) inspired” compounds with potential antitumor
activity, a series of 21 new CUR-BF 2 adducts and CURs bearing fluorine, trifluoromethylthio…

Predatory outer membrane vesicles (OMVs) secreted by myxobacteria fuse readily with the
outer membranes of Gram-negative bacteria, introducing toxic cargo into their prey. Here we …

Extracellular membrane vesicles are produced by all domains of life (bacteria, archaea and
eukaryotes). Bacterial extracellular vesicles (outer membrane vesicles or OMVs) are …

Peptide transporters 1 and 2 (PepT1 and PepT2) and peptide/histidine transporter 1 (PHT1)
are all members of the proton-coupled oligopeptide transporter family, which are important …

Annelida represents a large and morphologically diverse group of bilaterian organisms. The
recently published polychaete and leech genome sequences revealed an equally dynamic …

The myxobacteria are an order of abundant and virtually ubiquitous soil-dwelling
Deltaproteobacteria. They initially attracted scientific attention in the nineteenth century for their …