User profiles for A. T. Keinath
Alexandra T. KeinathAssistant Professor, University of Illinois Chicago Verified email at uic.edu Cited by 946 |
[PDF][PDF] The neurocognitive basis of spatial reorientation
… Introduction At some point in our lives, all of us have had the unsettling experience of losing
… or global positioning system, we must look out at the world and use perceptual information to …
… or global positioning system, we must look out at the world and use perceptual information to …
[HTML][HTML] The representation of context in mouse hippocampus is preserved despite neural drift
… This population-level structure is supported by heterogeneous patterns of activity at the
level of individual cells, where we observe evidence of a positive relationship between …
level of individual cells, where we observe evidence of a positive relationship between …
Making sense of the multiplicity and dynamics of navigational codes in the brain
… At the outset, we would like to note that this review is intended to serve as a record of the …
and discussed at the minisymposium on encoding of navigationally relevant variables at the …
and discussed at the minisymposium on encoding of navigationally relevant variables at the …
[HTML][HTML] Population dynamics of head-direction neurons during drift and reorientation
… During baseline recordings at the start of each session, we displayed a polarizing vertical
white stripe on the otherwise black LED screen. All subsequent testing involved the …
white stripe on the otherwise black LED screen. All subsequent testing involved the …
Human entorhinal cortex represents visual space using a boundary-anchored grid
… The value of this PM at each time point was the cosine of gaze-movement direction at that
… a(t) is the gaze-movement direction sampled at time t (30 Hz). This PM was downsampled to …
… a(t) is the gaze-movement direction sampled at time t (30 Hz). This PM was downsampled to …
Precise spatial coding is preserved along the longitudinal hippocampal axis
… white walls (animals were tested in the SEA at the beginning and at the end of the session);
this … Only sessions with at least 30 s of movement in the last 25% of the session, and at least …
this … Only sessions with at least 30 s of movement in the last 25% of the session, and at least …
[PDF][PDF] Environmental geometry aligns the hippocampal map during spatial reorientation
… The mechanisms underlying spatial reorientation have been at the heart of numerous
debates about the nature of cognition. Here, Keinath et al. show that after disorientation, the …
debates about the nature of cognition. Here, Keinath et al. show that after disorientation, the …
[HTML][HTML] Disruption of the grid cell network in a mouse model of early Alzheimer's disease
J Ying, AT Keinath, R Lavoie, E Vigneault… - Nature …, 2022 - nature.com
… Grid cell deficits emerged at the earliest incidence of Aβ fibril deposition and coincided with
impaired spatial memory performance in a path integration task. These results demonstrate …
impaired spatial memory performance in a path integration task. These results demonstrate …
Environmental deformations dynamically shift the grid cell spatial metric
… Our results do not rule out additional dynamics and mechanisms which may be at play during
environmental deformations. Indeed, it is likely that multiple mechanisms contribute to the …
environmental deformations. Indeed, it is likely that multiple mechanisms contribute to the …
Place recognition and heading retrieval are mediated by dissociable cognitive systems in mice
… Although our results might seem at first glance to fit more closely with the first view insofar
as we postulate the operation of independent mechanisms, one of which is especially …
as we postulate the operation of independent mechanisms, one of which is especially …