User profiles for A. T. Keinath

Alexandra T. Keinath

Assistant Professor, University of Illinois Chicago
Verified email at uic.edu
Cited by 946

[PDF][PDF] The neurocognitive basis of spatial reorientation

JB Julian, AT Keinath, SA Marchette, RA Epstein - Current Biology, 2018 - cell.com
… Introduction At some point in our lives, all of us have had the unsettling experience of losing
… or global positioning system, we must look out at the world and use perceptual information to …

[HTML][HTML] The representation of context in mouse hippocampus is preserved despite neural drift

AT Keinath, CA Mosser, MP Brandon - Nature Communications, 2022 - nature.com
… This population-level structure is supported by heterogeneous patterns of activity at the
level of individual cells, where we observe evidence of a positive relationship between …

Making sense of the multiplicity and dynamics of navigational codes in the brain

…, A Wikenheiser, JPG Noel, AT Keinath - Journal of …, 2022 - Soc Neuroscience
At the outset, we would like to note that this review is intended to serve as a record of the …
and discussed at the minisymposium on encoding of navigationally relevant variables at the …

[HTML][HTML] Population dynamics of head-direction neurons during drift and reorientation

Z Ajabi, AT Keinath, XX Wei, MP Brandon - Nature, 2023 - nature.com
… During baseline recordings at the start of each session, we displayed a polarizing vertical
white stripe on the otherwise black LED screen. All subsequent testing involved the …

Human entorhinal cortex represents visual space using a boundary-anchored grid

JB Julian, AT Keinath, G Frazzetta, RA Epstein - Nature neuroscience, 2018 - nature.com
… The value of this PM at each time point was the cosine of gaze-movement direction at that
… a(t) is the gaze-movement direction sampled at time t (30 Hz). This PM was downsampled to …

Precise spatial coding is preserved along the longitudinal hippocampal axis

AT Keinath, ME Wang, EG Wann, RK Yuan… - …, 2014 - Wiley Online Library
… white walls (animals were tested in the SEA at the beginning and at the end of the session);
this … Only sessions with at least 30 s of movement in the last 25% of the session, and at least …

[PDF][PDF] Environmental geometry aligns the hippocampal map during spatial reorientation

AT Keinath, JB Julian, RA Epstein, IA Muzzio - Current Biology, 2017 - cell.com
… The mechanisms underlying spatial reorientation have been at the heart of numerous
debates about the nature of cognition. Here, Keinath et al. show that after disorientation, the …

[HTML][HTML] Disruption of the grid cell network in a mouse model of early Alzheimer's disease

J Ying, AT Keinath, R Lavoie, E Vigneault… - Nature …, 2022 - nature.com
… Grid cell deficits emerged at the earliest incidence of Aβ fibril deposition and coincided with
impaired spatial memory performance in a path integration task. These results demonstrate …

Environmental deformations dynamically shift the grid cell spatial metric

AT Keinath, RA Epstein, V Balasubramanian - Elife, 2018 - elifesciences.org
… Our results do not rule out additional dynamics and mechanisms which may be at play during
environmental deformations. Indeed, it is likely that multiple mechanisms contribute to the …

Place recognition and heading retrieval are mediated by dissociable cognitive systems in mice

JB Julian, AT Keinath, IA Muzzio… - Proceedings of the …, 2015 - National Acad Sciences
… Although our results might seem at first glance to fit more closely with the first view insofar
as we postulate the operation of independent mechanisms, one of which is especially …