User profiles for A. Abdellaoui
Abdel AbdellaouiDepartment of Psychiatry, Amsterdam UMC, University of Amsterdam Verified email at amsterdamumc.nl Cited by 19228 |
[PDF][PDF] 15 years of GWAS discovery: realizing the promise
It has been 15 years since the advent of the genome-wide association study (GWAS) era.
Here, we review how this experimental design has realized its promise by facilitating an …
Here, we review how this experimental design has realized its promise by facilitating an …
Dissecting polygenic signals from genome-wide association studies on human behaviour
A Abdellaoui, KJH Verweij - Nature Human Behaviour, 2021 - nature.com
Genome-wide association studies on human behavioural traits are producing large amounts
of polygenic signals with significant predictive power and potentially useful biological clues. …
of polygenic signals with significant predictive power and potentially useful biological clues. …
Electronic structure and magnetic properties of quaternary Heusler alloys CoRhMnZ (Z= Al, Ga, Ge and Si) via first-principle calculations
M Benkabou, H Rached, A Abdellaoui… - Journal of Alloys and …, 2015 - Elsevier
First-principle calculations are performed to predict the electronic structure and elastic and
magnetic properties of CoRhMnZ (Z = Al, Ga, Ge and Si) Heusler alloys. The calculations …
magnetic properties of CoRhMnZ (Z = Al, Ga, Ge and Si) Heusler alloys. The calculations …
Genome-wide association study identifies 74 loci associated with educational attainment
Educational attainment is strongly influenced by social and other environmental factors, but
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …
genetic factors are estimated to account for at least 20% of the variation across individuals 1. …
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …
GWAS of 126,559 individuals identifies genetic variants associated with educational attainment
A genome-wide association study (GWAS) of educational attainment was conducted in a
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
Humans vary substantially in their willingness to take risks. In a combined sample of over 1
million individuals, we conducted genome-wide association studies (GWAS) of general risk …
million individuals, we conducted genome-wide association studies (GWAS) of general risk …
Polygenic risk scores for schizophrenia and bipolar disorder predict creativity
We tested whether polygenic risk scores for schizophrenia and bipolar disorder would
predict creativity. Higher scores were associated with artistic society membership or creative …
predict creativity. Higher scores were associated with artistic society membership or creative …
Heritability and genomics of gene expression in peripheral blood
We assessed gene expression profiles in 2,752 twins, using a classic twin design to quantify
expression heritability and quantitative trait loci (eQTLs) in peripheral blood. The most …
expression heritability and quantitative trait loci (eQTLs) in peripheral blood. The most …
Seventy-five genetic loci influencing the human red blood cell
Anaemia is a chief determinant of global ill health, contributing to cognitive impairment,
growth retardation and impaired physical capacity. To understand further the genetic factors …
growth retardation and impaired physical capacity. To understand further the genetic factors …