Urothelial carcinoma (UC), also referred to as transitional cell carcinoma (TCC), is the most
common bladder malignancy in both human and canine populations. In human UC, …

Over the last decade, the introduction of microarray technology has had a profound impact
on gene expression research. The publication of studies with dissimilar or altogether …

Although thousands of large intergenic non-coding RNAs (lincRNAs) have been identified
in mammals, few have been functionally characterized, leading to debate about their …

Single-nuclei RNA sequencing characterizes cell types at the gene level. However, compared
to single-cell approaches, many single-nuclei cDNAs are purely intronic, lack barcodes …

We have assessed the utility of RNA titration samples for evaluating microarray platform
performance and the impact of different normalization methods on the results obtained. As part …

Genome-editing technologies are currently being translated to the clinic. However, cellular
effects of the editing machinery have yet to be fully elucidated. Here, we performed global …

External RNA controls (ERCs), although important for microarray assay performance assessment,
have yet to be fully implemented in the research community. As part of the MicroArray …

Background Oncopanel genomic testing, which identifies important somatic variants, is
increasingly common in medical practice and especially in clinical trials. Currently, there is a …

Background Targeted sequencing using oncopanels requires comprehensive assessments
of accuracy and detection sensitivity to ensure analytical validity. By employing reference …

Background Highly multiplexed assays for quantitation of RNA transcripts are being used in
many areas of biology and medicine. Using data generated by these transcriptomic assays …