Complement system in neural synapse elimination in development and disease

J Presumey, AR Bialas, MC Carroll - Advances in immunology, 2017 - Elsevier
Recent discoveries implicate the classical complement cascade in normal brain development
and in disease. Complement proteins C1q, C3, and C4 participate in synapse elimination, …

[PDF][PDF] Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets

…, J Nemesh, K Shekhar, M Goldman, I Tirosh, AR Bialas… - Cell, 2015 - cell.com
Cells, the basic units of biological structure and function, vary broadly in type and state.
Single-cell genomics can characterize cell identity and function, but limitations of ease and scale …

Lessons in effector and NLR biology of plant-microbe systems

A Białas, EK Zess… - Molecular Plant …, 2018 - Am Phytopath Society
A diversity of plant-associated organisms secrete effectors—proteins and metabolites that
modulate plant physiology to favor host infection and colonization. However, effectors can also …

Schizophrenia risk from complex variation of complement component 4

A Sekar, AR Bialas, H De Rivera, A Davis… - Nature, 2016 - nature.com
Schizophrenia is a heritable brain illness with unknown pathogenic mechanisms.
Schizophrenia’s strongest genetic association at a population level involves variation in the major …

Nine things to know about elicitins

…, YF Dagdas, JC De la Concepcion, A Bialas… - New …, 2016 - Wiley Online Library
Elicitins are structurally conserved extracellular proteins in Phytophthora and Pythium oomycete
pathogen species. They were first described in the late 1980s as abundant proteins in …

Intermittency in multiparticle production at high energy

A Bialas, R Peschanski - Nuclear Physics B, 1988 - Elsevier
We present predictions of random cascading models for multiparticle production at high
energy. Standard and correlated factorial moments in rapidity are shown to provide stringent …

Retracted article: TGF-β signaling regulates neuronal C1q expression and developmental synaptic refinement

AR Bialas, B Stevens - Nature neuroscience, 2013 - nature.com
Immune molecules, including complement proteins C1q and C3, have emerged as critical
mediators of synaptic refinement and plasticity. Complement localizes to synapses and refines …

Moments of rapidity distributions as a measure of short-range fluctuations in high-energy collisions

A Bialas, R Peschanski - Nuclear Physics B, 1986 - Elsevier
It is proposed to study the dependence of factorial moments of the rapidity distribution on the
size δy of the resolution. It is shown that if the fluctuations are purely statistical no variation …

Microglia-dependent synapse loss in type I interferon-mediated lupus

AR Bialas, J Presumey, A Das, CE van der Poel… - Nature, 2017 - nature.com
Systemic lupus erythematosus (SLE) is an incurable autoimmune disease characterized by
autoantibody deposition in tissues such as kidney, skin and lungs. Notably, up to 75% of …

The PHOBOS detector at RHIC

…, S Basilev, R Baum, RR Betts, A Białas… - Nuclear Instruments and …, 2003 - Elsevier
This manuscript contains a detailed description of the PHOBOS experiment as it is configured
for the Year 2001 running period. It is capable of detecting charged particles over the full …