The GWAS Catalog delivers a high-quality curated collection of all published genome-wide
association studies enabling investigations to identify causal variants, understand disease …

The NHGRI-EBI GWAS Catalog ( www.ebi.ac.uk/gwas ) is a FAIR knowledgebase providing
detailed, structured, standardised and interoperable genome-wide association study (GWAS…

We present the Polygenic Score (PGS) Catalog ( https://www.PGSCatalog.org ), an open
resource of published scores (including variants, alleles and weights) and consistently curated …

The Open Targets Platform ( https://platform.opentargets.org/ ) is an open source resource to
systematically assist drug target identification and prioritisation using publicly available data…

Open Targets Genetics ( https://genetics.opentargets.org ) is an open-access integrative
resource that aggregates human GWAS and functional genomics data including gene …

Genome-wide association studies (GWASs) have identified many variants associated with
complex traits, but identifying the causal gene(s) is a major challenge. In the present study, we …

Adult-onset hearing loss is very common, but we know little about the underlying molecular
pathogenesis impeding the development of therapies. We took a genetic approach to identify …

The accurate description of ancestry is essential to interpret, access, and integrate human
genomics data, and to ensure that these benefit individuals from all ancestral backgrounds. …

Genome-wide association studies (GWASs) have enabled robust mapping of complex traits
in humans. The open sharing of GWAS summary statistics (SumStats) is essential in …

WBP 2 encodes the WW domain‐binding protein 2 that acts as a transcriptional coactivator
for estrogen receptor α ( ESR 1) and progesterone receptor ( PGR ). We reported that the loss …