User profiles for A. Ehrlicher

Allen Ehrlicher

McGill University, Harvard University, University of Leipzig, University of Texas
Verified email at mcgill.ca
Cited by 4838

[HTML][HTML] The forces behind cell movement

R Ananthakrishnan, A Ehrlicher - International journal of biological …, 2007 - ncbi.nlm.nih.gov
Cell movement is a complex phenomenon primarily driven by the actin network beneath the
cell membrane, and can be divided into three general components: protrusion of the leading …

Advancing the mechanical performance of glasses: perspectives and challenges

L Wondraczek, E Bouchbinder, A Ehrlicher… - Advanced …, 2022 - Wiley Online Library
Glasses are materials that lack a crystalline microstructure and long‐range atomic order.
Instead, they feature heterogeneity and disorder on superstructural scales, which have …

Can a collapse of global civilization be avoided?

PR Ehrlich, AH Ehrlich - Proceedings of the Royal …, 2013 - royalsocietypublishing.org
Environmental problems have contributed to numerous collapses of civilizations in the past.
Now, for the first time, a global collapse appears likely. Overpopulation, overconsumption by …

[HTML][HTML] Probing the stochastic, motor-driven properties of the cytoplasm using force spectrum microscopy

M Guo, AJ Ehrlicher, MH Jensen, M Renz, JR Moore… - Cell, 2014 - cell.com
Molecular motors in cells typically produce highly directed motion; however, the aggregate,
incoherent effect of all active processes also creates randomly fluctuating forces, which drive …

Cytoskeletal mechanics of proplatelet maturation and platelet release

…, MT Devine, JL Richardson, A Ehrlicher… - Journal of cell …, 2010 - rupress.org
Megakaryocytes generate platelets by remodeling their cytoplasm into long proplatelet
extensions, which serve as assembly lines for platelet production. Although the mechanics of …

[HTML][HTML] The role of vimentin intermediate filaments in cortical and cytoplasmic mechanics

M Guo, AJ Ehrlicher, S Mahammad, H Fabich… - Biophysical journal, 2013 - cell.com
The mechanical properties of a cell determine many aspects of its behavior, and these mechanics
are largely determined by the cytoskeleton. Although the contribution of actin filaments …

Controlled synthesis of cell-laden microgels by radical-free gelation in droplet microfluidics

T Rossow, JA Heyman, AJ Ehrlicher… - Journal of the …, 2012 - ACS Publications
Micrometer-sized hydrogel particles that contain living cells can be fabricated with exquisite
control through the use of droplet-based microfluidics and bioinert polymers such as …

Guiding neuronal growth with light

A Ehrlicher, T Betz, B Stuhrmann… - Proceedings of the …, 2002 - National Acad Sciences
Control over neuronal growth is a fundamental objective in neuroscience, cell biology,
developmental biology, biophysics, and biomedicine and is particularly important for the formation …

Mechanical strain in actin networks regulates FilGAP and integrin binding to filamin A

AJ Ehrlicher, F Nakamura, JH Hartwig, DA Weitz… - Nature, 2011 - nature.com
Mechanical stresses elicit cellular reactions mediated by chemical signals. Defective
responses to forces underlie human medical disorders 1 , 2 , 3 , 4 such as cardiac failure 5 and …

Alpha-actinin binding kinetics modulate cellular dynamics and force generation

AJ Ehrlicher, R Krishnan, M Guo… - Proceedings of the …, 2015 - National Acad Sciences
The actin cytoskeleton is a key element of cell structure and movement whose properties are
determined by a host of accessory proteins. Actin cross-linking proteins create a connected …