Organizing matter at the atomic scale is a central goal of nanotechnology. Bottom-up approaches,
in which molecular building blocks are programmed to assemble via supramolecular …

Self‐assembling polyhedral protein biomaterials have gained attention as engineering
targets owing to their naturally evolved sophisticated functions, ranging from protecting …

Membrane sculpting and transformation is essential for many cellular functions, thus being
largely regulated by self-assembling and self-organizing protein coats. Their functionality is …

Computationally designed multi-subunit assemblies have shown considerable promise for
a variety of applications, including a new generation of potent vaccines. One of the major …

The healthy growth and maintenance of a biological system depends on the precise spatial
organization of molecules within the cell through the dissipation of energy. Reaction–…

Computationally designed protein nanoparticles have recently emerged as a promising
platform for the development of new vaccines and biologics. For many applications, secretion of …

DNA origami nanotechnology is being increasingly used to mimic membrane-associated
biophysical phenomena. Although a variety of DNA origami nanostructures has already been …

DNA nanostructures offer the possibility to mimic functional biological membrane
components due to their nanometer-precise shape configurability and versatile biochemical …

DNA origami is a state-of-the-art technology that enables the fabrication of nano-objects with
defined shapes, to which functional moieties, such as lipophilic anchors, can be attached …

10.7554/eLife.24350.001 The cell membrane is a heterogeneously organized composite
with lipid-protein micro-domains. The contractile actin cortex may govern the lateral …