User profiles for A. McCaskie

Alex McCaskey

NVIDIA
Verified email at nvidia.com
Cited by 2062

[HTML][HTML] Systematic review and meta-analysis of the reliability and discriminative validity of cartilage compositional MRI in knee osteoarthritis

…, SBL Low, TO Smith, AP Toms, AW McCaskie… - Osteoarthritis and …, 2018 - Elsevier
Objective To assess reliability and discriminative validity of cartilage compositional magnetic
resonance imaging (MRI) in knee osteoarthritis (OA). Design The study was carried out per …

[PDF][PDF] Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

…, A Carr, P Deloukas, M Doherty, AW McCaskie… - Cell, 2021 - cell.com
Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide
association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and …

A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

…, M Kloppenburg, PA Lind, A McCaskie… - Annals of the …, 2014 - ard.bmj.com
Objectives Osteoarthritis (OA) is the most common form of arthritis with a clear genetic component.
To identify novel loci associated with hip OA we performed a meta-analysis of genome…

Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis

…, T Ingvarsson, H Jonsson, GC Babis, A McCaskie… - Nature …, 2018 - nature.com
Osteoarthritis is a common complex disease imposing a large public-health burden. Here,
we performed a genome-wide association study for osteoarthritis, using data across 16.5 …

Arthroscopic hip surgery compared with physiotherapy and activity modification for the treatment of symptomatic femoroacetabular impingement: multicentre …

…, S Wood, V Khanduja, TCB Pollard, AW McCaskie… - bmj, 2019 - bmj.com
Objective To compare arthroscopic hip surgery with physiotherapy and activity modification
for improving patient reported outcome measures in patients with symptomatic …

Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study

…, P Deloukas, M Doherty, A McCaskie… - Annals of the …, 2011 - ard.bmj.com
Objectives The genetic aetiology of osteoarthritis has not yet been elucidated. To enable a
well-powered genome-wide association study (GWAS) for osteoarthritis, the authors have …

The prevalence of osteoporosis in patients with severe hip and knee osteoarthritis awaiting joint arthroplasty

…, R Peaston, FN Birrell, AW McCaskie - Age and …, 2010 - academic.oup.com
Background: the presence of osteoporosis in patients with hip and knee osteoarthritis (OA)
has important implications for understanding disease progression and providing optimal …

[BOOK][B] Bailey & Love's short practice of surgery

NS Williams, PR O'connell, A McCaskie - 2018 - books.google.com
Bailey & Love is the world famous textbook of surgery. Its comprehensive coverage includes
the scientific basis of surgical practice, investigation, diagnosis, and pre-operative care. …

[HTML][HTML] Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis

…, RGHH Nelissen, I Meulenbelt, AW McCaskie… - Scientific reports, 2017 - nature.com
Osteoarthritis (OA) is a common disease characterized by cartilage degeneration and joint
remodeling. The underlying molecular changes underpinning disease progression are …

[HTML][HTML] Neuroarthropathy in diabetes: pathogenesis of Charcot arthropathy

SE Johnson-Lynn, AW McCaskie, AP Coll… - Bone & Joint …, 2018 - boneandjoint.org.uk
Charcot neuroarthropathy is a rare but serious complication of diabetes, causing progressive
destruction of the bones and joints of the foot leading to deformity, altered biomechanics …