Many signaling systems show adaptation—the ability to reset themselves after responding
to a stimulus. We computationally searched all possible three-node enzyme network …

When unfolded proteins accumulate to irremediably high levels within the endoplasmic
reticulum (ER), intracellular signaling pathways called the unfolded protein response (UPR) …

Traffic is constrained by the information involved in locating the receiver and the physical
distance between sender and receiver. We here focus on the former, and investigate traffic in …

Disruption of protein folding in the endoplasmic reticulum (ER) causes unfolded proteins to
accumulate, triggering the unfolded protein response (UPR). UPR outputs in turn decrease …

A two-dimensional small-world-type network, subject to spatial prisoners’ dilemma dynamics
and containing an influential node defined as a special node, with a finite density of …

Oscillations are commonly observed in cellular behavior and span a wide range of
timescales, from seconds in calcium signaling to 24 hours in circadian rhythms. In between lie …

Using each node’s degree as a proxy for its importance, the topological hierarchy of a complex
network is introduced and quantified. We propose a simple dynamical process used to …

Many toxin–antitoxin (TA) loci are known to strongly repress their own transcription. This
auto-inhibition is often called ‘conditional cooperativity’ as it relies on cooperative binding of TA …

High-resolution maps of embryonic development suggest that acquisition of cell identity is not
limited to canonical germ layers but proceeds via alternative routes. Despite evidence that …

We study Nowak and May’s spatial prisoners’ dilemma game driven by mutations (random
choices of suboptimal strategies) on empirical social networks. The time evolution of the …