The vitamin D endocrine system is involved in a wide variety of biological processes including
bone metabolism, modulation of the immune response, and regulation of cell proliferation …

Established guidelines for causal inference in epidemiological studies may be inappropriate
for genetic associations. A consensus process was used to develop guidance criteria for …

Osteoporosis is a common disease with a strong genetic component characterized by
reduced bone mass, defects in the microarchitecture of bone tissue, and an increased risk of …

Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density
lipoprotein cholesterol and triglycerides are among the most important risk factors for …

Breast cancer exhibits familial aggregation, consistent with variation in genetic susceptibility
to the disease. Known susceptibility genes account for less than 25% of the familial risk of …

By combining genome-wide association data from 8,130 individuals with type 2 diabetes (T2D)
and 38,987 controls of European descent and following up previously unidentified meta-…

We describe a new molecular approach to analyzing the genetic diversity of complex microbial
populations. This technique is based on the separation of polymerase chain reaction-…

Through genome-wide association meta-analyses of up to 133,010 individuals of European
ancestry without diabetes, including individuals newly genotyped using the Metabochip, we …

Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …

The incidence of all non-vertebral fractures, as well as the relation to bone mineral density (BMD),
was quantified in 7806 men and women from the Rotterdam Study, a prospective, …