Background Restless legs syndrome is a prevalent chronic neurological disorder with
potentially severe mental and physical health consequences. Clearer understanding of the …

Infectious diseases have a profound impact on our health and many studies suggest that
host genetics play a major role in the pathogenesis of most of them. We perform 23 genome-…

Here, we investigate how Candida albicans, the most prevalent human fungal pathogen,
protects itself from nitric oxide ( . NO), an antimicrobial compound produced by the innate …

Background Attention-deficit/hyperactivity disorder (ADHD) shows substantial heritability
and is two to seven times more common in male individuals than in female individuals. We …

Severe burn injuries have long been known to have a profound effect on metabolic
equilibrium that can persist after resolution of the cutaneous injuries. Following burn injury, …

Roughly one in three individuals is highly susceptible to motion sickness and yet the underlying
causes of this condition are not well understood. Despite high heritability, no associated …

The genetic basis of earlobe attachment has been a matter of debate since the early 20 th
century, such that geneticists argue both for and against polygenic inheritance. Recent genetic …

Progress identifying the genetic determinants of personality has historically been slow, with
candidate gene studies and small-scale genome-wide association studies yielding few …

The synthesis of tenoxicam, 4-hydroxy-2-methyl-JV-2-pyridyl-2H-thieno [2, 3-e]-l, 2-thiazine-3-carboxamide
1, 1-dioxide (le), and of the analogues with various residues on the ring …

During pregnancy, Plasmodium falciparum-infected erythrocytes cytoadhere to the placenta.
Infection is likely initiated at two sites where placental trophoblasts contact maternal blood: 1…